Neuropathic pain
L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas
XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …
several underlying pathophysiological mechanisms, some of which are still uncertain. The …
In vivo confocal microscopy of corneal nerves in health and disease
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
Current understanding of the mixed pain concept: a brief narrative review
R Freynhagen, HA Parada… - … medical research and …, 2019 - Taylor & Francis
Despite having been referenced in the literature for over a decade, the term “mixed pain”
has never been formally defined. The strict binary classification of pain as being either …
has never been formally defined. The strict binary classification of pain as being either …
New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine
H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
Emerging biomarkers, tools, and treatments for diabetic polyneuropathy
GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …
[HTML][HTML] Advances in screening, early diagnosis and accurate staging of diabetic neuropathy
J Carmichael, H Fadavi, F Ishibashi… - Frontiers in …, 2021 - frontiersin.org
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …
Early detection of nerve fiber loss by corneal confocal microscopy and skin biopsy in recently diagnosed type 2 diabetes
D Ziegler, N Papanas, A Zhivov, S Allgeier, K Winter… - Diabetes, 2014 - Am Diabetes Assoc
We sought to determine whether early nerve damage may be detected by corneal confocal
microscopy (CCM), skin biopsy, and neurophysiological tests in 86 recently diagnosed type …
microscopy (CCM), skin biopsy, and neurophysiological tests in 86 recently diagnosed type …
[HTML][HTML] Focus: Sensory biology and pain: Corneal innervation and sensation: The eye and beyond
AY Yang, J Chow, J Liu - The Yale journal of biology and medicine, 2018 - ncbi.nlm.nih.gov
The cornea is one of the most densely innervated and sensitive tissues in the body. In
addition to their important sensory functions, corneal nerves induce reflex tear production …
addition to their important sensory functions, corneal nerves induce reflex tear production …
Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres
J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …