Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

The discovery of the default mode network (DMN) has revolutionized our understanding of
the workings of the human brain. Here, I review developments that led to the discovery of the …

The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

The gut microbiota affects many important host functions, including the immune response
and the nervous system. However, while substantial progress has been made in growing …

Chronic stress and depressive-like behaviors in basic neuroscience research have been
associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss …

Cognitive neuroscience has traditionally focused on simple tasks, presented sparsely and
using abstract stimuli. While this approach has yielded fundamental insights into functional …

The mechanisms underlying the pathophysiology and treatment of depression and stress-
related disorders remain unclear, but studies in depressed patients and rodent models are …

Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their …

Background: Clinically significant anxiety and depression are common in patients with
cancer, and are associated with poor psychiatric and medical outcomes. Historical and …

Major depressive disorder (MDD) is common and disabling, but its neuropathophysiology
remains unclear. Most studies of functional brain networks in MDD have had limited …