NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors

B Meyer, T Peters - Angewandte Chemie International Edition, 2003 - Wiley Online Library
Binding events of ligands to receptors are the key for an understanding of biological
processes. Gaining insight into protein–protein and protein–ligand interactions in solution …

Natural protein proteinase inhibitors and their interaction with proteinases

W Bode, R Huber - European Journal of Biochemistry, 1992 - Wiley Online Library
The substrate‐like 'canonical'inhibition by the 'small'serine proteinase inhibitors and the
product‐like inhibition by the carboxypeptidase inhibitor have provided the only atomic …

[引用][C] Protein NMR Spectroscopy: Principles And Practice

J Cavanagh - 1996 - books.google.com
Protein NMR Spectroscopy: Principles and Practice combines a comprehensive theoretical
treatment of high resolution NMR spectroscopy with an extensive exposition of the …

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

DS Wishart, BD Sykes, FM Richards - Biochemistry, 1992 - ACS Publications
Materials and Methods Chemical Shift and Secondary Structure Assignments. Chemical shift
data were collected entirely from published sources. All proton chemical shift values were …

Temperature dependence of 1H chemical shifts in proteins

NJ Baxter, MP Williamson - Journal of biomolecular NMR, 1997 - Springer
Temperature coefficients have been measured by 2D NMR methods forthe amide and CαH
proton chemical shifts in two globularproteins, bovine pancreatic trypsin inhibitor and hen …

Protein hydration in aqueous solution

G Otting, E Liepinsh, K Wüthrich - Science, 1991 - science.org
High-resolution proton nuclear magnetic resonance studies of protein hydration in aqueous
solution show that there are two qualitatively different types of hydration sites. A well …

Solution structure of dengue virus capsid protein reveals another fold

L Ma, CT Jones, TD Groesch… - Proceedings of the …, 2004 - National Acad Sciences
Dengue virus is responsible for≈ 50–100 million infections, resulting in nearly 24,000
deaths annually. The capsid (C) protein of dengue virus is essential for specific …

Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by …

D Neri, T Szyperski, G Otting, H Senn, K Wuethrich - Biochemistry, 1989 - ACS Publications
Revised Manuscript Received July 11, 1989 abstract: Stereospecific* H and 13C NMR
assignments were made for the two diastereotopic methyl groups of the 14 valyl and leucyl …

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

D Baù, A Sanyal, BR Lajoie, E Capriotti… - Nature structural & …, 2011 - nature.com
We developed a general approach that combines chromosome conformation capture
carbon copy (5C) with the Integrated Modeling Platform (IMP) to generate high-resolution …

Inhibition of human leukocyte and porcine pancreatic elastase by homologues of bovine pancreatic trypsin inhibitor

JAE Kraunsoe, TDW Claridge, G Lowe - Biochemistry, 1996 - ACS Publications
The interactions of three BPTI homologues with human leukocyte elastase and porcine
pancreatic elastase have been investigated. The principal mutation in determining the …