New developments in RiPP discovery, enzymology and engineering
M Montalbán-López, TA Scott, S Ramesh… - Natural product …, 2021 - pubs.rsc.org
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …
JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
Proteases involved in leader peptide removal during RiPP biosynthesis
SM Eslami, WA van der Donk - ACS Bio & Med Chem Au, 2023 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) have received
much attention in recent years because of their promising bioactivities and the portability of …
much attention in recent years because of their promising bioactivities and the portability of …
Unveiling the biosynthetic pathway of the ribosomally synthesized and post‐translationally modified peptide ustiloxin B in filamentous fungi
Y Ye, A Minami, Y Igarashi, M Izumikawa… - Angewandte …, 2016 - Wiley Online Library
The biosynthetic machinery of the first fungal ribosomally synthesized and post‐
translationally modified peptide (RiPP) ustiloxin B was elucidated through a series of gene …
translationally modified peptide (RiPP) ustiloxin B was elucidated through a series of gene …
Chemical repertoire and biosynthetic machinery of the Aspergillus flavus secondary metabolome: A review
Filamentous fungi represent a rich source of extrolites, including secondary metabolites
(SMs) comprising a great variety of astonishing structures and interesting bioactivities. State …
(SMs) comprising a great variety of astonishing structures and interesting bioactivities. State …
Heterologous biosynthesis as a platform for producing new generation natural products
Highlights•Natural products include numerous societally valuable compounds.•Medicinally
relevant natural products include many clinical antibiotics.•Escherichia coli is a common …
relevant natural products include many clinical antibiotics.•Escherichia coli is a common …
Heterologous production of asperipin-2a: proposal for sequential oxidative macrocyclization by a fungi-specific DUF3328 oxidase
Asperipin-2a is a ribosomally synthesized and post-translationally modified peptide isolated
from Asperigillus flavus. Herein, we report the heterologous production of asperipin-2a and …
from Asperigillus flavus. Herein, we report the heterologous production of asperipin-2a and …
Aspergillus flavus secondary metabolites: more than just aflatoxins
Aspergillus flavus is best known for producing the family of potent carcinogenic secondary
metabolites known as aflatoxins. However, this opportunistic plant and animal pathogen …
metabolites known as aflatoxins. However, this opportunistic plant and animal pathogen …
Discovery of novel fungal RiPP biosynthetic pathways and their application for the development of peptide therapeutics
E Vogt, M Künzler - Applied microbiology and biotechnology, 2019 - Springer
Bioactive peptide natural products are an important source of therapeutics. Prominent
examples are the antibiotic penicillin and the immunosuppressant cyclosporine which are …
examples are the antibiotic penicillin and the immunosuppressant cyclosporine which are …