Models of Intrauterine growth restriction and fetal programming in rabbits

J Lopez‐Tello, M Arias‐Alvarez… - Molecular …, 2019 - Wiley Online Library
Intrauterine growth restriction (IUGR) affects approximately 10% of human pregnancies
globally and has immediate and life‐long consequences for offspring health. However, the …

Detection and assessment of brain injury in the growth-restricted fetus and neonate

A Malhotra, M Ditchfield, MC Fahey… - Pediatric …, 2017 - nature.com
Fetal growth restriction (FGR) is a common complication of pregnancy and, in severe cases,
is associated with elevated rates of perinatal mortality, neonatal morbidity, and poor …

Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR

DS Hunter, SJ Hazel, KL Kind, JA Owens… - Physiology & …, 2016 - Elsevier
IUGR in humans is associated with impaired pre-and postnatal neurodevelopment, and
subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and …

Neurodevelopment outcome in children with fetal growth restriction at six years of age: a retrospective cohort study

MJ Benítez Marín, JA Blanco Elena… - International Journal of …, 2022 - mdpi.com
Objective: This study aimed to describe neurodevelopment in fetal growth restriction children
at the age of six. Secondly, we tried to demonstrate influencing factors that can improve or …

Intrauterine growth restriction and development of the hippocampus: implications for learning and memory in children and adolescents

C Gilchrist, A Cumberland, D Walker… - The Lancet Child & …, 2018 - thelancet.com
Intrauterine growth restriction (IUGR) is often the result of compromised placental function
and suboptimal uteroplacental blood flow. Children born with IUGR have impaired cognitive …

Animal models of fetal medicine and obstetrics

MD Andersen, AKO Alstrup, CS Duvald… - … animal models of …, 2018 - books.google.com
Animal models remain essential to understand the fundamental mechanisms occurring in
fetal medicine and obstetric diseases, such as intrauterine growth restriction, preeclampsia …

Metabolomic identification of placental alterations in fetal growth restriction

RO Bahado-Singh, O Turkoglu, A Yilmaz… - The Journal of …, 2022 - Taylor & Francis
Introduction Fetal growth restriction (FGR), viz., birth weight< 10th percentile is a common
pregnancy complication which increases the risk of adverse fetal and newborn outcomes …

Structural brain changes during the neonatal period in a rabbit model of intrauterine growth restriction

L Pla, M Illa, C Loreiro, MC Lopez… - Developmental …, 2021 - karger.com
Background: Intrauterine growth restriction (IUGR) is associated with abnormal
neurodevelopment, but the associated structural brain changes are poorly documented. The …

Gestational 1-nitropyrene exposure causes gender-specific impairments on postnatal growth and neurobehavioral development in mice

R Li, X Wang, B Wang, J Li, Y Song, B Luo… - Ecotoxicology and …, 2019 - Elsevier
Nitropyrene (1-NP), a typical nitrated polycyclic aromatic hydrocarbon, is widely distributed
in the environment and is well known for its mutagenic effects. Recently, we found that …

[HTML][HTML] Advanced MRI analysis to detect white matter brain injury in growth restricted newborn lambs

A Malhotra, T Sepehrizadeh, T Dhollander, D Wright… - NeuroImage: Clinical, 2019 - Elsevier
Background Fetal growth restriction (FGR) is a serious pregnancy complication associated
with increased risk of adverse neurodevelopment and neuromorbidity. Current imaging …