Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Forces are increasingly recognized as major regulators of cell structure and function, and
the mechanical properties of cells are essential to the mechanisms by which cells sense …

Cellular interactions with the extracellular matrix and with neighboring cells profoundly
influence a variety of signaling events including those involved in mitogenesis, survival, and …

Cell migration is a process which is essential during embryonic development, throughout
adult life and in some pathological conditions. Cadherins, and more specifically the neural …

The study of protein glycosylation has lagged far behind the progress of current proteomics
because of the enormous complexity, wide dynamic range distribution and low …

The mammalian heart is crafted from a few progenitor cells that are subject to rapidly
changing sets of instructions from their environment and from within. These instructions …

Connections between the cytoskeleton and intercellular junctions profoundly influence cell
shape and motility. It is becoming increasingly clear that in addition to structural functions …

A defining feature of biology is the use of a multiscale architecture, ranging from molecular
networks to cells, tissues, organs, whole bodies, and swarms. Crucially however, biology is …

The heart develops from two bilateral heart fields that are formed during early gastrulation. In
recent years, signaling pathways that specify cardiac mesoderm have been extensively …

Embryonic morphogenesis occurs along three orthogonal axes. While the patterning of the
anterior–posterior and dorsal–ventral axes has been increasingly well characterized, the left …