[HTML][HTML] Duchenne muscular dystrophy
Duchenne muscular dystrophy is a severe, progressive, muscle-wasting disease that leads
to difficulties with movement and, eventually, to the need for assisted ventilation and …
to difficulties with movement and, eventually, to the need for assisted ventilation and …
[HTML][HTML] ROS and diseases: Role in metabolism and energy supply
S Yang, G Lian - Molecular and cellular biochemistry, 2020 - Springer
Researches dedicated to reactive oxygen species (ROS) had been performed for decades,
yet the outcomes remain controversial. With the relentless effort of studies, researchers have …
yet the outcomes remain controversial. With the relentless effort of studies, researchers have …
[HTML][HTML] The role of oxidative stress in skeletal muscle myogenesis and muscle disease
D Lian, MM Chen, H Wu, S Deng, X Hu - Antioxidants, 2022 - mdpi.com
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle
cause it to continuously produce moderate levels of oxidant species, such as reactive …
cause it to continuously produce moderate levels of oxidant species, such as reactive …
Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor
R Hajian, S Balderston, T Tran, T DeBoer… - Nature biomedical …, 2019 - nature.com
Most methods for the detection of nucleic acids require many reagents and expensive and
bulky instrumentation. Here, we report the development and testing of a graphene-based …
bulky instrumentation. Here, we report the development and testing of a graphene-based …
Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy
DE Frank, FJ Schnell, C Akana, SH El-Husayni… - Neurology, 2020 - AAN Enterprises
Objective To report safety, pharmacokinetics, exon 53 skipping, and dystrophin expression
in golodirsen-treated patients with Duchenne muscular dystrophy (DMD) amenable to exon …
in golodirsen-treated patients with Duchenne muscular dystrophy (DMD) amenable to exon …
[HTML][HTML] Gene therapy for Duchenne muscular dystrophy
N Elangkovan, G Dickson - Journal of neuromuscular …, 2021 - content.iospress.com
Duchenne muscular dystrophy (DMD) is an X-linked, muscle wasting disease that affects 1
in 5000 males. Affected individuals become wheelchair bound by the age of twelve and …
in 5000 males. Affected individuals become wheelchair bound by the age of twelve and …
Emerging therapies for Duchenne muscular dystrophy
Duchenne muscular dystrophy is an X-linked disease caused by the absence of functional
dystrophin in the muscle cells. Major advances have led to the development of gene …
dystrophin in the muscle cells. Major advances have led to the development of gene …
CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells
YL Min, H Li, C Rodriguez-Caycedo, AA Mireault… - Science …, 2019 - science.org
Mutations in the dystrophin gene cause Duchenne muscular dystrophy (DMD), which is
characterized by lethal degeneration of cardiac and skeletal muscles. Mutations that delete …
characterized by lethal degeneration of cardiac and skeletal muscles. Mutations that delete …
ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy
Mitochondrial permeability transition pore (MPTP) formation contributes to ischemia-
reperfusion injury in the heart and several degenerative diseases, including muscular …
reperfusion injury in the heart and several degenerative diseases, including muscular …
[HTML][HTML] Abnormal calcium handling in Duchenne muscular dystrophy: mechanisms and potential therapies
Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …