Hepatocellular carcinoma (HCC) is the most frequent liver cancer with high lethality and low
five-year survival rates leading to a substantial worldwide burden for healthcare systems …

Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality and has an
increasing incidence worldwide. HCC can be induced by multiple etiologies, is influenced …

Hepatocellular carcinoma is one of the most prevalent and lethal cancers with limited
therapeutic options. Pathogenesis of this disease involves tumor hypoxia and the activation …

Liver fibrosis is a potentially reversible pathophysiological event, leading to excess
deposition of extracellular matrix (ECM) components and taking place as the net result of …

Hepatocellular carcinoma (HCC) is the fifth most common and the third most deadly
malignant tumor worldwide. Hypoxia and related oxidative stress are heavily involved in the …

Hepatocellular carcinoma (HCC) is a male‐dominant cancer, and androgen receptor (AR)
has been linked to the pathogenesis of HCC. However, AR expression and its precise role in …

Despite therapeutic interventions for glioblastoma (GBM), cancer stem cells (CSCs) drive
recurrence. The precise mechanisms underlying CSC resistance, namely inhibition of cell …

Human SERPINB3 and SERPINB4 are evolutionary duplicated serine/cysteine protease
inhibitors. Genomic analysis indicates that these paralogous genes were encoded from …

Pancreatic ductal adenocarcinoma (PDAC) exhibits distinct molecular subtypes:
classical/progenitor and basal-like/squamous. Our study aimed to identify genes contributing …

Oncostatin M (OSM) is a pleiotropic cytokine of the interleukin (IL)‐6 family that contributes to
the progression of chronic liver disease. Here we investigated the role of OSM in the …