An understanding of mechanism-based approaches for 1, 3, 4-oxadiazole scaffolds as cytotoxic agents and enzyme inhibitors
The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …
new drugs to treat cancer. There has been a significant improvement in understanding the …
A Novel Approach to Prepare Cellulose-g-Hydroxyapatite Originated from Natural Sources as an Efficient Adsorbent for Heavy Metals: Batch Adsorption Optimization …
In the present research, we describe a novel approach for in situ synthesis of cellulose
microfibrils-grafted-hydroxyapatite (CMFs-g-HAPN (8%)) as an adsorbent using phosphate …
microfibrils-grafted-hydroxyapatite (CMFs-g-HAPN (8%)) as an adsorbent using phosphate …
Green and efficient one-pot three-component synthesis of novel drug-like furo [2, 3-d] pyrimidines as potential active site inhibitors and putative allosteric hotspots …
H Mousavi, B Zeynizadeh, M Rimaz - Bioorganic Chemistry, 2023 - Elsevier
In this paper, an environmentally benign, convenient, and efficient one-pot three-component
reaction has been developed for the regioselective synthesis of novel 5-aroyl (or …
reaction has been developed for the regioselective synthesis of novel 5-aroyl (or …
Fixed-bed adsorption of Pb (ii) and Cu (ii) from multi-metal aqueous systems onto cellulose-g-hydroxyapatite granules: optimization using response surface …
SE Marrane, K Dânoun, Y Essamlali, S Aboulhrouz… - RSC …, 2023 - pubs.rsc.org
We prepared cellulose microfibrils-g-hydroxyapatite (CMFs-g-HAPN (8%)) in a granular
form. We evaluated the ability of these granules to eliminate Pb (II) and Cu (II) ions from …
form. We evaluated the ability of these granules to eliminate Pb (II) and Cu (II) ions from …
New 1, 2, 3-triazoles from (R)-carvone: Synthesis, DFT mechanistic study and in vitro cytotoxic evaluation
A Oubella, A Bimoussa, A N'ait Oussidi, M Fawzi… - Molecules, 2022 - mdpi.com
Aseries of novel 1, 4-disubstituted 1, 2, 3-triazoles were synthesized from an (R)-carvone
terminal alkyne derivative via a Cu (I)-catalyzed azide–alkyne cycloaddition reaction using …
terminal alkyne derivative via a Cu (I)-catalyzed azide–alkyne cycloaddition reaction using …
Synthesis, molecular docking, molecular dynamics and ADMET prediction studies of novel (S)-Verbenone-Arylidene-Isoxazoline hybrids
M Fawzi, Y Laamari, SJ Koyambo-Konzapa… - Journal of Molecular …, 2024 - Elsevier
The main objective of this work was to develop novel hybrid compounds from naturally
occurring (S)-Verbenone. This last was used as a starting material to prepare new …
occurring (S)-Verbenone. This last was used as a starting material to prepare new …
Synthesis and Antiviral Efficacy of Pyrimidine Analogs Targeting Viral Pathways
N Jeelan Basha, TL Chandana - ChemistrySelect, 2023 - Wiley Online Library
To date, viruses are known to cause chronic to acute pathogenesis. Nevertheless, antiviral
drugs have been known for their medicinal applications for the last few decades to treat …
drugs have been known for their medicinal applications for the last few decades to treat …
New 3-(2-methoxyphenyl)-isoxazole-carvone: synthesis, spectroscopic characterization, and prevention of carbon steel corrosion in hydrochloric acid
A novel mono-isoxazole was synthesized from (R)-Carvone and O-methoxy-benzaldoxime,
via a [3+ 2] cycloaddition reaction. The newly obtained mono-isoxazole has been fully …
via a [3+ 2] cycloaddition reaction. The newly obtained mono-isoxazole has been fully …
Synthesis, characterization, molecular docking, and anticancer activities of new 1, 3, 4-oxadiazole-5-fluorocytosine hybrid derivatives
Abstract Analogs of pyrimidine and 1, 3, 4-oxadiazole are two well established class of
molecules proven as potent antiviral and anticancer agents in the pharmaceutical industry …
molecules proven as potent antiviral and anticancer agents in the pharmaceutical industry …
Synthesis, spectroscopic characterization, and prevention of carbon steel corrosion in hydrochloric acid of a new bis-isoxazoline-carvone
Abstract A series of C (3)-mono-substituted isoxazoline of type mono-and bis-isoxazoline,
have been prepared from (R)-carvone 1 in a two-step procedure. First,(R)-carvone was …
have been prepared from (R)-carvone 1 in a two-step procedure. First,(R)-carvone was …