Maintenance of gastrointestinal health is challenging as it requires balancing multifaceted
processes within the highly complex and dynamic ecosystem of the gastrointestinal tract …

Cancer neuroscience has emerged as a burgeoning field for the investigation of cancer-
nervous system interactions. Perineural invasion (PNI) is defined as the presence of cancer …

Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

Biglycan (BGN) is a proteoglycan with branch chains and highly expressed in enteric
neurons in the tumor tissue of colorectal cancer (CRC), which is negatively associated with …

Colorectal cancer (CRC) is a multifactorial and multistage process that occurs due to both
genetic and epigenetic variations in normal epithelial cells. Analysis of the CRC epigenome …

Collagen type IV α1 chain (COL4A1) is a collagen protein that acts as a tumor‑promoting
factor in several types of cancer. However, the role and the potential mechanisms involving …

The tumor microenvironment corresponds to a complex mixture of bioactive products
released by local and recruited cells whose normal functions have been “corrupted” by cues …

The resistance to anoikis plays a critical role in the metastatic progression of various types of
malignancies, including gastric cancer (GC). Nevertheless, the precise mechanism behind …

Simple Summary Nidogen1 (NID1) is a component of the extracellular matrix and basement
membranes. NID1 represents a linker between laminins, collagens, proteoglycans and cell …

Epigenetic modifications have long been recognized as an essential level in transcriptional
regulation linking behavior and environmental conditions or stimuli with biological …