The liver performs numerous vital functions, including the detoxification of blood before
access to the brain while simultaneously secreting and internalizing scores of proteins and …

The involvement of free radical mechanisms in the pathogenesis of alcoholic liver disease
(ALD) is demonstrated by the detection of lipid peroxidation markers in the liver and the …

Scavenger receptors constitute a large family of proteins that are structurally diverse and
participate in a wide range of biological functions. These receptors are expressed …

The study of hepatic fibrosis, or scarring in response to chronic liver injury, has witnessed
tremendous progress in the past two decades. Clarification of the cellular sources of scar …

Liver fibrosis is caused by many chronic diseases. Liver injury results in activation of
collagen‐producing cells and excessive deposition of extracellular matrix proteins. This …

Background & Aims: Recent research has suggested that apoptosis could be involved in the
development of fibrosis, although it is generally considered to be a mechanism of cell …

Abstract The Ashwell–Morell receptor (AMR) of hepatocytes, originally termed the hepatic
asialoglycoprotein receptor, was the first cellular receptor to be identified and isolated and …

Extensive evidence indicates that ethanol (alcohol) has immunomodulatory properties.
Many of its effects on innate immune response are dose dependent, with acute or moderate …

The ability of a pathogen to evade host immunity successfully, in contrast to the host's
capacity to defend itself against a foreign invader, is a complex struggle, in which …

The process of dead cell clearance by phagocytic cells, called efferocytosis, prevents
inflammatory cell necrosis and promotes resolution and repair. Defective efferocytosis …