Energy demand of neurons in brain that is covered by glucose supply from the blood is
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …

Abstract Both type 1 (T1DM) and type 2 diabetes mellitus (T2DM) have been associated with
reduced performance on multiple domains of cognitive function and with evidence of …

Clinical studies suggest a link between type 2 diabetes mellitus (T2DM) and insulin
resistance (IR) and cognitive dysfunction, but there are significant gaps in our knowledge of …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its major
pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from …

Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

The aim of this paper is to provide a comprehensive review of the epidemiological evidence
linking type 2 diabetes mellitus and its related conditions, including obesity …

Background Chronic high-fat diet (HFD) consumption caused not only obese-insulin
resistance, but also cognitive decline and microglial hyperactivity. Modified gut microbiota by …

The associations between consumption of a high-fat or 'Western'diet and metabolic
disorders such as obesity, diabetes, and cardiovascular disease have long been recognized …

Alzheimer's disease (AD) is the sixth leading cause of death in the USA today; therefore, it is
imperative that public health initiatives and clinical strategies are developed to prevent and …

Abstract Dipeptidyl peptidase-4 inhibitor (vildagliptin) has been shown to exert beneficial
effects on insulin sensitivity and neuroprotection in obese-insulin resistance. Recent studies …