Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …

The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir
is a variety of small mammals. Although infection of these natural hosts does not lead to …

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of
Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes …

This study demonstrates a strict temporal requirement for a virulence determinant of the
Lyme disease spirochete Borrelia burgdorferi during a unique point in its natural infection …

Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …

Borrelia burgdorferi (Bb) adapts to its arthropod and mammalian hosts by altering its
transcriptional and antigenic profiles in response to environmental signals associated with …