Man has moved rapidly from the hunter–gatherer environment to the living conditions of the
rich industrialized countries. The hygiene hypothesis suggests that the resulting changed …

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells
activated by chronic Helicobacter pylori (H. pylori) infection. Polymorphisms of these …

Cancer cachexia is a multi-factorial syndrome that encompasses a spectrum from early
weight loss (pre-cachexia) to a state of severe incapacity incompatible with life. The …

Background Accurate prediction of outcome in advanced non-small-cell lung cancer (nsclc)
remains challenging. Even within the same stage and treatment group, survival and …

Cancer is generally recognized as an age-related disease. In fact, incidence and mortality
rates of most human cancers increase consistently with age up to 90 years, but they plateau …

Although relevant achievements in the treatment of cancer have been obtained, some
barriers still remain in the prevention and treatments of cancer comorbidities, including …

Inflammation is one of the early phases in the development of gastric cancer. Therefore,
several studies have examined the association of polymorphisms in tumour-necrosis factor …

IL-6 is critical for tumorigenesis. However, previous studies on the association of IL-6
promoter polymorphisms with predisposition to different cancer types are somewhat …

Cachexia is an important clinical problem affecting up to two thirds of cancer patients. It
results from anorexia and metabolic change and leads to loss of both adipose tissue and …

Flow cytometry was originally established as an automated method for measuring optical or
fluorescence characteristics of cells or particles in suspension. With the enormous increase …