SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …

A narrative review of coronavirus disease 2019 (COVID-19): clinical, epidemiological characteristics, and systemic manifestations

A Krishnan, JP Hamilton, SA Alqahtani… - Internal and emergency …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which
has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in …

Retinal involvement and ocular findings in COVID-19 pneumonia patients

MP Pirraglia, G Ceccarelli, A Cerini, G Visioli… - Scientific Reports, 2020 - nature.com
Abstract Changes in immune and coagulation systems and possible viral spread through the
blood–brain barrier have been described in SARS-CoV-2 infection. In this study, we …

SARS-CoV-2 on ocular surfaces in a cohort of patients with COVID-19 from the Lombardy region, Italy

C Azzolini, S Donati, E Premi, A Baj… - JAMA …, 2021 - jamanetwork.com
Importance Since February 2020, coronavirus disease 2019 (COVID-19) has spread rapidly
all over the world, with an epidemiological cluster in Lombardy, Italy. The viral …

TFOS lifestyle: Impact of societal challenges on the ocular surface

F Stapleton, JC Abad, S Barabino, A Burnett, G Iyer… - The Ocular Surface, 2023 - Elsevier
Societal factors associated with ocular surface diseases were mapped using a framework to
characterize the relationship between the individual, their health and environment. The …

Presence of SARS-CoV-2 RNA in the cornea of viremic patients with COVID-19

M Casagrande, A Fitzek, MS Spitzer… - JAMA …, 2021 - jamanetwork.com
Importance Current recommendations are to avoid tissue for corneal transplant from donors
with coronavirus disease 2019 (COVID-19) or those who were recently exposed to COVID …

Systemic diseases and the cornea

R Shah, C Amador, K Tormanen, S Ghiam… - Experimental eye …, 2021 - Elsevier
There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

M Ostaszewski, A Niarakis, A Mazein… - Molecular systems …, 2021 - embopress.org
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …

SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium

AZ Eriksen, R Møller, B Makovoz, SA Uhl… - Cell stem cell, 2021 - cell.com
The SARS-CoV-2 pandemic has caused unparalleled disruption of global behavior and
significant loss of life. To minimize SARS-CoV-2 spread, understanding the mechanisms of …

Update and recommendations for ocular manifestations of COVID-19 in adults and children: a narrative review

V Danthuluri, MB Grant - Ophthalmology and Therapy, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has instigated severe global
turmoil both medically and socioeconomically. Research continues to rapidly develop in …