[HTML][HTML] Mechanisms of ketogenic diet action

SA Masino, JM Rho - Jasper's Basic Mechanisms of the Epilepsies …, 2012 - ncbi.nlm.nih.gov
Within the past two decades, interest in understanding the therapeutic mechanisms of
ketogenic diet (KD) action has grown steadily. Expanded knowledge about underlying …

The interaction between sleep and epilepsy

AH Roliz, S Kothare - Current Neurology and Neuroscience Reports, 2022 - Springer
Abstract Purpose of Review To review the mutual interactions between sleep and epilepsy,
including mechanisms of epileptogenesis, the relationship between sleep apnea and …

Role of the orexin system in the bidirectional relation between sleep and epilepsy: New chances for patients with epilepsy by the antagonism to orexin receptors?

C Berteotti, C Calvello, C Liguori - Epilepsia, 2023 - Wiley Online Library
Epilepsy is a common neurological disorder, affecting patients of all ages, reducing the
quality of life, and associated with several comorbidities. Sleep impairment is a frequent …

Effects of antiepileptic drugs on sleep architecture parameters in adults

BMS Carvalho, J Chaves, AM da Silva - Sleep Science, 2022 - thieme-connect.com
Objectives Physiological and restorative sleep is fundamental for physical and mental well-
being. Polysomnography parameters are objective methods to access sleep structure …

Orexin receptor antagonists in the pathophysiology and treatment of sleep disorders and epilepsy

M Sheibani, M Shayan, M Khalilzadeh, M Ghasemi… - Neuropeptides, 2023 - Elsevier
The correlation between sleep and epilepsy has been argued over the past decades among
scientists. Although the similarities and contrasts between sleep and epilepsy had been …

Impedance rhythms in human limbic system

F Mivalt, V Kremen, V Sladky, J Cui… - Journal of …, 2023 - Soc Neuroscience
The impedance is a fundamental electrical property of brain tissue, playing a crucial role in
shaping the characteristics of local field potentials, the extent of ephaptic coupling, and the …

[HTML][HTML] Perampanel effect on sleep architecture in patients with epilepsy

R Rocamora, I Álvarez, B Chavarría, A Principe - Seizure, 2020 - Elsevier
Purpose Among patients with epilepsy, sleep disturbances can worsen seizure control. This
prospective open-label study determined the effect of the antiepileptic drug perampanel on …

Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice

HM Roundtree, TA Simeone, C Johnson, SA Matthews… - Sleep, 2016 - academic.oup.com
Abstract Study Objective: Comorbid sleep disorders occur in approximately one-third of
people with epilepsy. Seizures and sleep disorders have an interdependent relationship …

Toward rational design of electrical stimulation strategies for epilepsy control

S Sunderam, B Gluckman, D Reato, M Bikson - Epilepsy & Behavior, 2010 - Elsevier
Electrical stimulation is emerging as a viable alternative for patients with epilepsy whose
seizures are not alleviated by drugs or surgery. Its attractions are temporal and spatial …

Insomnia in neurological disorders: Prevalence, mechanisms, impact and treatment approaches

R de Bergeyck, PA Geoffroy - Revue Neurologique, 2023 - Elsevier
Insomnia is more prevalent in neurological disorders compared to the general population,
with rates ranging from 11 to 74.2% in neurodegenerative disorders, 20 to 37% in vascular …