Oxytocin, dopamine, and opioid interactions underlying pair bonding: highlighting a potential role for microglia

MK Loth, ZR Donaldson - Endocrinology, 2021 - academic.oup.com
Pair bonds represent some of the strongest attachments we form as humans. These
relationships positively modulate health and well-being. Conversely, the loss of a spouse is …

Variation, plasticity, and alternative mating tactics: revisiting what we know about the socially monogamous prairie vole

JE Madrid, KJ Parker, AG Ophir - Advances in the Study of Behavior, 2020 - Elsevier
Comparative research on arvicoline rodents has provided important insights into the
neurobiological basis of social bonds. Within the last two decades, the prairie vole (Microtus …

Paternal deprivation impairs social behavior putatively via epigenetic modification to lateral septum vasopressin receptor

AM Kelly, JY Ong, RA Witmer, AG Ophir - Science advances, 2020 - science.org
Although it is well appreciated that the early-life social environment asserts subsequent long-
term consequences on offspring brain and behavior, the specific mechanisms that account …

Differential fate between oxytocin and vasopressin cells in the developing mouse brain

A Soumier, M Habart, G Lio, C Demily, A Sirigu - IScience, 2022 - cell.com
Oxytocin (OXT) and arginine vasopressin (AVP), two neuropeptides involved in socio-
emotional behaviors have been anatomically defined in the adult brain. Yet their spatial …

Oxytocin receptor gene loss influences expression of the oxytocin gene in C57BL/6J mice in a sex‐and age‐dependent manner

R Vaidyanathan, EAD Hammock - Journal of …, 2020 - Wiley Online Library
Parental care and sensory stimulation are critical environmental factors that influence
oxytocin (OXT) and its receptor (OXTR). Because developmental Oxt mRNA expression is …

Distribution of vasopressin and oxytocin neurons in the basal forebrain and midbrain of spiny mice (Acomys cahirinus)

AM Kelly, AW Seifert - Neuroscience, 2021 - Elsevier
The nonapeptides vasopressin (VP) and oxytocin (OT) are present in some form in most
vertebrates. VP and OT play critical roles in modulating physiology and are well-studied for …

Species-typical group size differentially influences social reward neural circuitry during nonreproductive social interactions

JAG Abreu, AE Rosenberg, BA Fricker, KJ Wallace… - Iscience, 2022 - cell.com
We investigated whether nonreproductive social interactions may be rewarding for colonial
but not non-colonial species. We found that the colonial spiny mouse (Acomys cahirinus) is …

Paternal absence and increased caregiving independently and interactively shape the development of male prairie voles at subadult and adult life stages

LC Hiura, VA Lazaro, AG Ophir - Hormones and Behavior, 2024 - Elsevier
The influence of maternal caregiving is a powerful force on offspring development. The
absence of a father during early life in biparental species also has profound implications for …

Leveraging the unique social organization of California mice to study circuit-specific effects of oxytocin on behavior

AA Lake, BC Trainor - Hormones and Behavior, 2024 - Elsevier
Oxytocin is a versatile neuropeptide that modulates many different forms of social behavior.
Recent hypotheses pose that oxytocin enhances the salience of rewarding and aversive …

Plasticity in parental behavior and vasopressin: responses to co-parenting, pup age, and an acute stressor are experience-dependent

LC Hiura, VA Lazaro, AG Ophir - Frontiers in Behavioral …, 2023 - frontiersin.org
Introduction The impact of variation in parental caregiving has lasting implications for the
development of offspring. However, the ways in which parents impact each other in the …