The centrosome is a non-membrane-bound organelle that is conserved across most animal
cells and serves various functions throughout the cell cycle. In dividing cells, the centrosome …

Chromosome segregation in female germ cells and early embryonic blastomeres is known
to be highly prone to errors. The resulting aneuploidy is therefore the most frequent cause of …

Family with sequence similarity 161 (Fam161) is an ancient family of microtubule-binding
proteins located at the centriole and cilium transition zone (TZ) lumen that exhibit rapid …

There is a well–established link between abnormal sperm chromatin states and poor
motility, however, how these two processes are interdependent is unknown. Here, we …

Centrioles form centrosomes that organize microtubules, assist in cell structure, and
nucleate cilia that provide motility and sensation. Within the sperm, the centrosome consists …