Sequencing DNA with nanopores: Troubles and biases
C Delahaye, J Nicolas - PloS one, 2021 - journals.plos.org
Oxford Nanopore Technologies'(ONT) long read sequencers offer access to longer DNA
fragments than previous sequencer generations, at the cost of a higher error rate. While …
fragments than previous sequencer generations, at the cost of a higher error rate. While …
Epitranscriptomics in parasitic protists: role of RNA chemical modifications in posttranscriptional gene regulation
C Catacalos, A Krohannon, S Somalraju… - PLoS …, 2022 - journals.plos.org
“Epitranscriptomics” is the new RNA code that represents an ensemble of posttranscriptional
RNA chemical modifications, which can precisely coordinate gene expression and …
RNA chemical modifications, which can precisely coordinate gene expression and …
Straglr: discovering and genotyping tandem repeat expansions using whole genome long-read sequences
Tandem repeat (TR) expansion is the underlying cause of over 40 neurological disorders.
Long-read sequencing offers an exciting avenue over conventional technologies for …
Long-read sequencing offers an exciting avenue over conventional technologies for …
A mixed community of skin microbiome representatives influences cutaneous processes more than individual members
Background Skin, the largest organ of the human body by weight, hosts a diversity of
microorganisms that can influence health. The microbial residents of the skin are now …
microorganisms that can influence health. The microbial residents of the skin are now …
MTG-Link: leveraging barcode information from linked-reads to assemble specific loci
A Guichard, F Legeai, D Tagu, C Lemaitre - BMC bioinformatics, 2023 - Springer
Background Local assembly with short and long reads has proven to be very useful in many
applications: reconstruction of the sequence of a locus of interest, gap-filling in draft …
applications: reconstruction of the sequence of a locus of interest, gap-filling in draft …
Emergence of carbapenem resistance in persistent Shewanella algae bacteremia: the role of pdsS G547W mutation in adaptive subpopulation dynamics
This study elucidates the in vivo genetic mechanisms contributing to the emerging
resistance to carbapenem in Shewanella algae through a lens of adaptive microbial …
resistance to carbapenem in Shewanella algae through a lens of adaptive microbial …
Evaluating coverage bias in next-generation sequencing of Escherichia coli
Whole-genome sequencing is essential to many facets of infectious disease research.
However, technical limitations such as bias in coverage and tagmentation, and difficulties …
However, technical limitations such as bias in coverage and tagmentation, and difficulties …