[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

A systematic review of skin ageing genes: gene pleiotropy and genes on the chromosomal band 16q24. 3 may drive skin ageing

JY Ng, FT Chew - Scientific Reports, 2022 - nature.com
Skin ageing is the result of intrinsic genetic and extrinsic lifestyle factors. However, there is
no consensus on skin ageing phenotypes and ways to quantify them. In this systematic …

Comparisons between wrinkles and photo-ageing detected and self-reported by the participant or identified by trained assessors reveal insights from Chinese …

JY Ng, H Zhou, T Li, FT Chew - Journal of Physiological Anthropology, 2024 - Springer
Background Changes develop on the facial skin as a person ages. Other than chronological
time, it has been discovered that gender, ethnicity, air pollution, smoking, nutrition, and sun …

Fine Wrinkle Improvement through Bioactive Materials That Modulate EDAR and BNC2 Gene Expression

S Lee, S Ye, M Kim, H Lee, SH Jun, NG Kang - Biomolecules, 2024 - mdpi.com
Skin aging is a multifaceted biological phenomenon influenced by a combination of intrinsic
or extrinsic factors. There is an increasing interest in anti-aging materials including …

Clinical Assessment, Diagnosis, and Management of Infraorbital Wrinkles and Pigmentation

G Rathore, K Das, M Landau, I Verner… - Dermatologic …, 2024 - derm.theclinics.com
The skin around the eyes is one of the most highly sensitive areas of the face that is
susceptible to senility and senescence, resulting in wrinkles and hyperpigmentation. This is …

Neanderthal introgression in SCN9A impacts mechanical pain sensitivity

P Faux, L Ding, LM Ramirez-Aristeguieta… - Communications …, 2023 - nature.com
Abstract The Nav1. 7 voltage-gated sodium channel plays a key role in nociception. Three
functional variants in the SCN9A gene (encoding M932L, V991L, and D1908G in Nav1. 7) …

Comparisons between Caucasian‐validated photo‐numeric scales and Korean‐validated photo‐numeric scales for photo‐ageing. Insights from the Singapore …

JY Ng, H Zhou, T Li, FT Chew - Skin Research and Technology, 2024 - Wiley Online Library
Background Photo‐ageing is a form of skin ageing which affects the entire face. A photo‐
aged skin has a diverse variety of wrinkles and dyspigmentation all over the face. Here, we …

Genetic analysis of perceived youthfulness reveals differences in how men's and women's age is assessed

N Ingold, M Seviiri, JS Ong, S Gordon, RE Neale… - Journal of Investigative …, 2024 - Elsevier
Skin aging is a natural process that occurs over time but can be accelerated by sun
exposure. Measuring skin age in a large population can provide insight into the extent of …

The Keratinocyte in the Picture Cutaneous Melanoma Microenvironment

R Marrapodi, B Bellei - Cancers, 2024 - mdpi.com
Simple Summary The tumor environment is the place where the tumor resides implying that
it might evolve in the role of disease progression, particularly in the phase of tumor …

A gel-forming α-MSH analog promotes lasting melanogenesis

CL Chang, Z Cai, SYT Hsu - European Journal of Pharmacology, 2023 - Elsevier
The α-MSH peptide plays a significant role in the regulation of pigmentation via the
melanocortin 1 receptor (MC1R). It increases the DNA repair capacity of melanocytes and …