The absolute reliance of the mammalian brain on oxygen to generate ATP renders it acutely
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …

Obstructive sleep apnea (OSA) is a prevalent sleep disorder considered as an independent
risk factor for cardiovascular consequences, such as systemic arterial hypertension …

Background Intermittent hypoxia applied at rest or in combination with exercise promotes
multiple beneficial adaptations with regard to performance and health in humans. It was …

Oxygen is vital for cellular metabolism; therefore, the hypoxic conditions encountered at high
altitude affect all physiological functions. Acute hypoxia activates the adrenergic system and …

Aim Intermittent hypoxia (IH) is considered to be a major contributor to obstructive sleep
apnoea-related cardiovascular consequences. The present meta-analysis aimed to assess …

Purpose Main purposes of pre-acclimatization by hypoxia conditioning (HC) are the
prevention of high-altitude illnesses and maintenance of aerobic exercise performance …

Obstructive sleep apnea (OSA) is now recognized as an independent and important risk
factor for cardiovascular diseases such as hypertension, coronary heart disease, heart …

New Findings What is the topic of this review? This review examines the notion that
obstructive sleep apnoea (OSA) and intermittent hypoxia (IH) have hormetic effects on …

Central nervous system diseases are among the most disabling in the world.
Neuroprotection and brain recovery from either acute or chronic neurodegeneration still …

Hypoxia, defined as a reduced oxygen availability, can be observed in many tissues in
response to various physiological and pathological conditions. As a hallmark of the altitude …