[HTML][HTML] Hypoxia and brain aging: Neurodegeneration or neuroprotection?
The absolute reliance of the mammalian brain on oxygen to generate ATP renders it acutely
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …
Chronic intermittent hypoxia and obstructive sleep apnea: an experimental and clinical approach
E Sforza, F Roche - Hypoxia, 2016 - Taylor & Francis
Obstructive sleep apnea (OSA) is a prevalent sleep disorder considered as an independent
risk factor for cardiovascular consequences, such as systemic arterial hypertension …
risk factor for cardiovascular consequences, such as systemic arterial hypertension …
[HTML][HTML] Effects of intermittent hypoxia–hyperoxia on performance-and health-related outcomes in humans: A systematic review
Background Intermittent hypoxia applied at rest or in combination with exercise promotes
multiple beneficial adaptations with regard to performance and health in humans. It was …
multiple beneficial adaptations with regard to performance and health in humans. It was …
Cardiovascular physiology and pathophysiology at high altitude
JP Richalet, E Hermand, FJ Lhuissier - Nature Reviews Cardiology, 2024 - nature.com
Oxygen is vital for cellular metabolism; therefore, the hypoxic conditions encountered at high
altitude affect all physiological functions. Acute hypoxia activates the adrenergic system and …
altitude affect all physiological functions. Acute hypoxia activates the adrenergic system and …
Cardiac consequences of intermittent hypoxia: a matter of dose? A systematic review and meta-analysis in rodents
E Belaidi, C Khouri, O Harki, S Baillieul… - European …, 2022 - Eur Respiratory Soc
Aim Intermittent hypoxia (IH) is considered to be a major contributor to obstructive sleep
apnoea-related cardiovascular consequences. The present meta-analysis aimed to assess …
apnoea-related cardiovascular consequences. The present meta-analysis aimed to assess …
[HTML][HTML] Hypoxia conditioning for high-altitude pre-acclimatization
M Burtscher, GP Millet, J Burtscher - Journal of Science in Sport and …, 2022 - Springer
Purpose Main purposes of pre-acclimatization by hypoxia conditioning (HC) are the
prevention of high-altitude illnesses and maintenance of aerobic exercise performance …
prevention of high-altitude illnesses and maintenance of aerobic exercise performance …
Targeting the ROS-HIF-1-endothelin axis as a therapeutic approach for the treatment of obstructive sleep apnea-related cardiovascular complications
E Belaidi, J Morand, E Gras, JL Pépin… - Pharmacology & …, 2016 - Elsevier
Obstructive sleep apnea (OSA) is now recognized as an independent and important risk
factor for cardiovascular diseases such as hypertension, coronary heart disease, heart …
factor for cardiovascular diseases such as hypertension, coronary heart disease, heart …
Impact of obstructive sleep apnoea and intermittent hypoxia on cardiovascular and cerebrovascular regulation
AE Beaudin, X Waltz, PJ Hanly… - Experimental …, 2017 - Wiley Online Library
New Findings What is the topic of this review? This review examines the notion that
obstructive sleep apnoea (OSA) and intermittent hypoxia (IH) have hormetic effects on …
obstructive sleep apnoea (OSA) and intermittent hypoxia (IH) have hormetic effects on …
Hypoxic conditioning and the central nervous system: A new therapeutic opportunity for brain and spinal cord injuries?
S Baillieul, S Chacaroun, S Doutreleau… - Experimental …, 2017 - journals.sagepub.com
Central nervous system diseases are among the most disabling in the world.
Neuroprotection and brain recovery from either acute or chronic neurodegeneration still …
Neuroprotection and brain recovery from either acute or chronic neurodegeneration still …
[HTML][HTML] Altitude, exercise, and skeletal muscle angio-adaptive responses to hypoxia: a complex story
P Lemieux, O Birot - Frontiers in Physiology, 2021 - frontiersin.org
Hypoxia, defined as a reduced oxygen availability, can be observed in many tissues in
response to various physiological and pathological conditions. As a hallmark of the altitude …
response to various physiological and pathological conditions. As a hallmark of the altitude …