The neuromuscular junction: roles in aging and neuromuscular disease
SR Iyer, SB Shah, RM Lovering - International journal of molecular …, 2021 - mdpi.com
The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …
Duchenne muscular dystrophy: pathogenesis and promising therapies
M Chang, Y Cai, Z Gao, X Chen, B Liu, C Zhang… - Journal of …, 2023 - Springer
Duchenne muscular dystrophy (DMD) is a severe, progressive, muscle-wasting disease,
characterized by progressive deterioration of skeletal muscle that causes rapid loss of …
characterized by progressive deterioration of skeletal muscle that causes rapid loss of …
[HTML][HTML] Advancing neural regeneration via adaptable hydrogels: Enriched with Mg2+ and silk fibroin to facilitate endogenous cell infiltration and macrophage …
Y Gao, Y Wang, J Zhang, M Zhang, C Dai, Y Zhang… - Bioactive Materials, 2024 - Elsevier
Peripheral nerve injury is a complex and challenging medical condition due to the limited
ability of nerves to regenerate, resulting in the loss of both sensory and motor function …
ability of nerves to regenerate, resulting in the loss of both sensory and motor function …
Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia
S Chiappalupi, G Sorci, A Vukasinovic… - Journal of cachexia …, 2020 - Wiley Online Library
Background Cachexia, a multifactorial syndrome affecting more than 50% of patients with
advanced cancer and responsible for~ 20% of cancer‐associated deaths, is still a poorly …
advanced cancer and responsible for~ 20% of cancer‐associated deaths, is still a poorly …
Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation
A Osseni, A Ravel-Chapuis, E Belotti, I Scionti… - Nature …, 2022 - nature.com
The absence of dystrophin in Duchenne muscular dystrophy disrupts the dystrophin-
associated glycoprotein complex resulting in skeletal muscle fiber fragility and atrophy …
associated glycoprotein complex resulting in skeletal muscle fiber fragility and atrophy …
Pre-and postsynaptic changes in the neuromuscular junction in dystrophic mice
Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which
weakness, increased susceptibility to muscle injury, and inadequate repair appear to …
weakness, increased susceptibility to muscle injury, and inadequate repair appear to …
Neuromuscular Development and Disease: Learning From in vitro and in vivo Models
Z Fralish, EM Lotz, T Chavez, A Khodabukus… - Frontiers in cell and …, 2021 - frontiersin.org
The neuromuscular junction (NMJ) is a specialized cholinergic synaptic interface between a
motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into …
motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into …
Secondary denervation is a chronic pathophysiologic sequela of volumetric muscle loss
JR Sorensen, DB Hoffman… - Journal of Applied …, 2021 - journals.physiology.org
Volumetric muscle loss (VML) is the traumatic loss of muscle tissue that results in long-term
functional impairments. Despite the loss of myofibers, there remains an unexplained …
functional impairments. Despite the loss of myofibers, there remains an unexplained …
Breathing in Duchenne muscular dystrophy: Translation to therapy
DZ Mhandire, DP Burns, AL Roger… - The Journal of …, 2022 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is an X‐linked neuromuscular disease caused by a
deficiency in dystrophin–a structural protein which stabilises muscle during contraction …
deficiency in dystrophin–a structural protein which stabilises muscle during contraction …
Regulation of satellite cells functions during skeletal muscle regeneration: a critical step in physiological and pathological conditions
G Careccia, L Mangiavini, F Cirillo - International Journal of Molecular …, 2023 - mdpi.com
Skeletal muscle regeneration is a complex process involving the generation of new
myofibers after trauma, competitive physical activity, or disease. In this context, adult skeletal …
myofibers after trauma, competitive physical activity, or disease. In this context, adult skeletal …