Maternal folic acid supplementation mediates offspring health via DNA methylation
HY Liu, SM Liu, YZ Zhang - Reproductive Sciences, 2020 - Springer
The clinical significance of periconceptional folic acid supplementation (FAS) in the
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …
Abnormal methylation caused by folic acid deficiency in neural tube defects
R Cao, J Xie, L Zhang - Open Life Sciences, 2022 - degruyter.com
Neural tube closure disorders, including anencephaly, spina bifida, and encephalocele,
cause neural tube defects (NTDs). This congenital disability remained not only a major …
cause neural tube defects (NTDs). This congenital disability remained not only a major …
Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a …
Prenatal inorganic arsenic (iAs) exposure influences the expression of critical genes and
proteins associated with adverse outcomes in newborns, in part through epigenetic …
proteins associated with adverse outcomes in newborns, in part through epigenetic …
Aberrant methylation of Pax3 gene and neural tube defects in association with exposure to polycyclic aromatic hydrocarbons
Abstract Background Neural tube defects (NTDs) are common and severe congenital
malformations. Pax3 is an essential gene for neural tube closure in mice but it is unknown …
malformations. Pax3 is an essential gene for neural tube closure in mice but it is unknown …
Fetal DNA hypermethylation in tight junction pathway is associated with neural tube defects: A genome-wide DNA methylation analysis
L Wang, S Lin, J Zhang, T Tian, L Jin, A Ren - Epigenetics, 2017 - Taylor & Francis
Neural tube defects (NTDs) are a spectrum of severe congenital malformations of fusion
failure of the neural tube during early embryogenesis. Evidence on aberrant DNA …
failure of the neural tube during early embryogenesis. Evidence on aberrant DNA …
TRIM4 is associated with neural tube defects based on genome-wide DNA methylation analysis
H Zhang, Y Guo, H Gu, X Wei, W Ma, D Liu, K Yu… - Clinical …, 2019 - Springer
Abstract Background Neural tube defects (NTDs) are complex abnormalities associated with
gene-environment interactions. The underlying cause has not been determined. Methods …
gene-environment interactions. The underlying cause has not been determined. Methods …
Low folate concentration impacts mismatch repair deficiency in neural tube defects
Aim: To know the cause of sequence variants in neural tube defect (NTD). Materials &
methods: We sequenced genes implicated in neural tube closure (NTC) in a Chinese cohort …
methods: We sequenced genes implicated in neural tube closure (NTC) in a Chinese cohort …
Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects
T Tian, L Wang, Y Shen, B Zhang, RH Finnell… - Epigenomics, 2018 - Future Medicine
Aim: To investigate the relationship between GRHL3 methylation and the etiology of neural
tube defects (NTDs). Materials & methods: Analyze data from a genome-wide DNA …
tube defects (NTDs). Materials & methods: Analyze data from a genome-wide DNA …
Ectopic cross-talk between thyroid and retinoic acid signaling: a possible etiology for spinal neural tube defects
Previous studies have highlighted the connections between neural tube defects (NTDs) and
both thyroid hormones (TH) and vitamin A. However, whether the two hormonal signaling …
both thyroid hormones (TH) and vitamin A. However, whether the two hormonal signaling …
Embryonic exposure to decitabine induces multiple neural tube defects in developing zebrafish
V Rajesh, PK Divya - Fish Physiology and Biochemistry, 2023 - Springer
Neural tube defects are severe congenital disorders of the central nervous system that
originate during embryonic development when the neural tube fails to close completely. It …
originate during embryonic development when the neural tube fails to close completely. It …