This review discussed and in particular emphasis the potential cellular pathways and the
biological processes involved that lead to homocysteine-induced endothelial dysfunction, in …

This review discusses the pathophysiology, epidemiology, risk factors, classification, clinical
evaluation, and current non-operative and operative treatment of hemorrhoids. Hemorrhoids …

Hemorrhoidal disease is a fairly common and debilitating clinical entity. Despite centuries' of
attempts to shed light on its pathophysiology, to cure those affected and to improve sufferers' …

There is growing interest in using functional foods or nutraceuticals for the prevention and
treatment of hypertension or high blood pressure. Although numerous preventive and …

The cardioprotective effects of dietary nitrate from beetroot in healthy and hypertensive
individuals are undeniable and irrefutable. Nitrate and nitrate-derived nitrite are precursors …

Vascular endothelium plays a key role in the local regulation of vascular tone and vascular
architecture by release of vasodilator and vasoconstrictor substances, as well as factors with …

Aim: To investigate the effects of glucagon-like peptide-1 (GLP-1) on endothelial NO
synthase (eNOS) in human umbilical vein endothelial cells (HUVECs), and elucidate …

The vascular endothelium constitutes approximately 1% of body mass (1kg) and has a
surface area of approximately 5000m2. The endothelium is a multifunctional endocrine …

Bilateral isometric handgrip (IHG) training lowers resting arterial blood pressure (BP) in
medicated hypertensives. Numerous mechanisms have been suggested, but have yet to be …

An explosion in global epidemic of type 2 diabetes mellitus poses major rise in cases with
vascular endothelial dysfunction ranging from micro-(retinopathy, nephropathy and …