Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Obesity has become a global epidemic and contributes to the increasing burden of type 2
diabetes, cardiovascular disease, stroke, some types of cancer, and premature death …

Mutations in PCSK1 cause monogenic obesity. To assess the contribution of PCSK1 to
polygenic obesity risk, we genotyped tag SNPs in a total of 13,659 individuals of European …

The article focuses on the role of genetic polymorphisms in periodontitis. The dynamics
between host immune responses and oral bacteria is discussed for a better understanding …

Evidence continues to accumulate on the rising burden of diabetes mellitus at a higher pace
in Africa. In a series of two papers, we sought to summarise recent evidence on diabetes …

Africa is the ultimate source of modern humans and as such harbors more genetic variation
than any other continent. For this reason, studies of the patterns of genetic variation in …

Abstract Recently, the rs6232 (N221D) and rs6235 (S690T) SNPs in the PCSK1 gene were
associated with obesity in a meta-analysis comprising more than 13 000 individuals of …

The burdens of type 2 diabetes (T2D) and cardiovascular diseases (CVD) are increasing in
Africa. T2D and CVD are the result of the complex interaction between inherited …

Objective The prevalence of obesity varies between ethnic groups. No genome‐wide
association study (GWAS) for body mass index (BMI) has been conducted in continental …