Inositol Trisphosphate Receptor Ca2+ Release Channels

JK Foskett, C White, KH Cheung… - Physiological …, 2007 - journals.physiology.org
The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …

Inositol 1, 4, 5-trisphosphate receptors as signal integrators

RL Patterson, D Boehning… - Annual review of …, 2004 - annualreviews.org
▪ Abstract The inositol 1, 4, 5 trisphosphate (IP3) receptor (IP3R) is a Ca2+ release channel
that responds to the second messenger IP3. Exquisite modulation of intracellular Ca2+ …

A comprehensive pathway map of epidermal growth factor receptor signaling

K Oda, Y Matsuoka, A Funahashi… - Molecular systems …, 2005 - embopress.org
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important
pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells …

Molecular properties of inositol 1, 4, 5-trisphosphate receptors

S Patel, SK Joseph, AP Thomas - Cell calcium, 1999 - Elsevier
The receptors for the second messenger inositol 1, 4, 5-trisphosphate (IP3) constitute a
family of Ca2+ channels responsible for the mobilization of intracellular Ca2+ stores. Three …

[HTML][HTML] Inositol 1, 4, 5-trisphosphate receptor-isoform diversity in cell death and survival

H Ivanova, T Vervliet, L Missiaen, JB Parys… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Cell-death and-survival decisions are critically controlled by intracellular Ca 2+ homeostasis
and dynamics at the level of the endoplasmic reticulum (ER). Inositol 1, 4, 5-trisphosphate …

Reading the patterns in living cells —the physics of ca2+ signaling

M Falcke - Advances in physics, 2004 - Taylor & Francis
Ca2+ is one of the most important messengers. It transmits signals inside living cells and
takes part in intercellular coordination. The dynamics of the Ca2+ concentration shows a …

Systems-level identification of PKA-dependent signaling in epithelial cells

K Isobe, HJ Jung, CR Yang… - Proceedings of the …, 2017 - National Acad Sciences
G protein stimulatory α-subunit (Gαs)-coupled heptahelical receptors regulate cell processes
largely through activation of protein kinase A (PKA). To identify signaling processes …

Expression of inositol trisphosphate receptors

CW Taylor, AA Genazzani, SA Morris - Cell calcium, 1999 - Elsevier
Inositol 1, 4, 5-trisphosphate (IP3) receptors are the intracellular Ca2+ channels most
commonly involved in allowing receptors in the plasma membrane to stimulate release of …

Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis

S Marchi, M Marinello, A Bononi, M Bonora… - Cell death & …, 2012 - nature.com
Ca 2+ transfer from endoplasmic reticulum (ER) to mitochondria can trigger apoptotic
pathways by inducing release of mitochondrial pro-apoptotic factors. Three different types of …

[HTML][HTML] Regulation of inositol 1, 4, 5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation

V Vanderheyden, B Devogelaere, L Missiaen… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The inositol 1, 4, 5-trisphosphate (IP3) receptor (IP3R) is a universal intracellular Ca2+-
release channel. It is activated after cell stimulation and plays a crucial role in the initiation …