Epithelial–mesenchymal transition (EMT) is a complex molecular program that regulates
changes in cell morphology and function during embryogenesis and tissue development …

The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP)
pathways intersect at multiple signaling hubs and cooperatively or counteractively …

Cholangiocarcinoma (CCA) is an aggressive tumor with a poor prognosis due to its late
clinical presentation and the lack of effective non-surgical therapies. Unfortunately, most of …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Epithelial-to-mesenchymal transition (EMT) represents conversion of an epithelial cell in an
elongated cell with mesenchymal phenotype, which can occur in physiologic and pathologic …

Cholangiocarcinoma (CCA) is a deadly disease. While surgery may attain cure in a minor
fraction of cases, therapeutic options in either the adjuvant or advanced setting are limited …

Bone morphogenetic proteins (BMPs) play important roles in embryonic and postnatal
development by regulating cell differentiation, proliferation, motility, and survival, thus …

Cholangiocarcinoma (CCA) is the second most common type of liver cancer, and is highly
aggressive with very poor prognosis. CCA is classified into intrahepatic cholangiocarcinoma …

Tumor growth and metastatic dissemination rely on cellular plasticity. Among the different
phenotypes acquired by cancer cells, epithelial to mesenchymal transition (EMT) has been …

STUDY QUESTION Does the upregulation of the zinc finger E-box binding homeobox 2
(ZEB2) transcription factor in human trophoblast cells lead to alterations in gene expression …