Leukemia inhibitory factor: roles in embryo implantation and in nonhormonal contraception

N Salleh, N Giribabu - The Scientific World Journal, 2014 - Wiley Online Library
Leukaemia inhibitory factor (LIF) plays an indispensible role in embryo implantation.
Aberrant LIF production is linked to implantation failure. LIF regulates multiple processes …

In vitro models of the human endometrium: evolution and application for women's health

HC Fitzgerald, DJ Schust, TE Spencer - Biology of reproduction, 2021 - academic.oup.com
The endometrium is the inner lining of the uterus that undergoes complex regeneration and
differentiation during the human menstrual cycle. The process of endometrial shedding …

Self-renewing endometrial epithelial organoids of the human uterus

HC Fitzgerald, P Dhakal, SK Behura… - Proceedings of the …, 2019 - National Acad Sciences
The human endometrium is essential in providing the site for implantation and maintaining
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …

Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success

AM Kelleher, J Milano-Foster, SK Behura… - Nature …, 2018 - nature.com
Uterine glands are essential for pregnancy establishment. By employing forkhead box A2
(FOXA2)-deficient mouse models coupled with leukemia inhibitory factor (LIF) repletion, we …

The multifaceted actions of leukaemia inhibitory factor in mediating uterine receptivity and embryo implantation

GX Rosario, CL Stewart - American Journal of Reproductive …, 2016 - Wiley Online Library
Embryo implantation is mediated by the combined actions of the ovarian hormones E2 and
P4 on the uterus. In addition, the pro‐inflammatory cytokine, leukaemia inhibitory factor (LIF) …

[HTML][HTML] Endometrial BCL6 testing for the prediction of in vitro fertilization outcomes: a cohort study

LD Almquist, CE Likes, B Stone, KR Brown, R Savaris… - Fertility and sterility, 2017 - Elsevier
Objective To evaluate endometrial BCL6 expression as a prognostic biomarker for IVF
outcome in women with unexplained infertility (UI) before ET. Design Prospective cohort …

[HTML][HTML] Prospective assessment of midsecretory endometrial leukemia inhibitor factor expression versus ανβ3 testing in women with unexplained infertility

JM Franasiak, KJ Holoch, L Yuan, DP Schammel… - Fertility and sterility, 2014 - Elsevier
Objective To evaluate endometrial leukemia inhibitor factor (LIF) expression as a marker of
endometrial receptivity in women with unexplained infertility (UI). Design Prospective case …

Assessing receptivity in the endometrium: the need for a rapid, non-invasive test

TA Edgell, LJF Rombauts, LA Salamonsen - Reproductive Biomedicine …, 2013 - Elsevier
Successful implantation of an embryo into the uterus requires synchrony between the
blastocyst and the endometrium. Endometrial preparedness, or receptivity, occurs only for a …

Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental …

A Yaghoobi, Y Nazerian, AZ Meymand… - Frontiers in Cell and …, 2023 - frontiersin.org
Assisted reproductive techniques as a new regenerative medicine approach have
significantly contributed to solving infertility problems that affect approximately 15% of …

Insufficient angiogenesis: cause of abnormally thin endometrium in subfertile patients?

J Alfer, L Happel, R Dittrich… - Geburtshilfe und …, 2017 - thieme-connect.com
Introduction This study investigated subfertile patients with abnormally thin endometrium
after infertility treatment. As they had adequate serum concentrations of hormones, an …