The role of adipokines in chronic inflammation

P Mancuso - ImmunoTargets and therapy, 2016 - Taylor & Francis
Adipose tissue has traditionally been defined as connective tissue that stores excess
calories in the form of triacylglycerol. However, the physiologic functions attributed to …

Obesity and asthma

DA Beuther, ST Weiss, ER Sutherland - American journal of …, 2006 - atsjournals.org
Asthma and obesity are prevalent disorders, each with a significant public health impact,
and a large and growing body of literature suggests an association between the two. The …

[HTML][HTML] Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production

V Sencio, A Barthelemy, LP Tavares, MG Machado… - Cell reports, 2020 - cell.com
Secondary bacterial infections often complicate viral respiratory infections. We hypothesize
that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor …

An official American Thoracic Society Workshop report: obesity and asthma

AE Dixon, F Holguin, A Sood, CM Salome… - Proceedings of the …, 2010 - atsjournals.org
Rationale: The developed world is currently facing an epidemic of obesity. With the
increased prevalence of obesity has come the recognition that obesity is a risk factor for …

Leptin and inflammation

N Iikuni, QL Kwan Lam, L Lu… - Current immunology …, 2008 - ingentaconnect.com
The past few years of research on leptin have provided important information on the link
between metabolism and immune homeostasis. Adipocytes influence not only the endocrine …

[HTML][HTML] Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus

AG Smith, PA Sheridan, JB Harp, MA Beck - The Journal of nutrition, 2007 - Elsevier
Obesity is associated with an impaired immune response, an increased susceptibility to
bacterial infection, and a chronic increase in proinflammatory cytokines such as IL-6 and …

Asthma and obesity

LP Boulet - Clinical & Experimental Allergy, 2013 - Wiley Online Library
The prevalence and incidence of asthma have increased among obese children and adults,
particularly among women. Obesity seems to be a predisposing factor for the development …

Diet-induced obesity in mice causes changes in immune responses and bone loss manifested by bacterial challenge

S Amar, Q Zhou… - Proceedings of the …, 2007 - National Acad Sciences
Obesity has been suggested to be associated with an increased susceptibility to bacterial
infection. However, few studies have examined the effect of obesity on the immune response …

Leptin functions in infectious diseases

R Maurya, P Bhattacharya, R Dey… - Frontiers in …, 2018 - frontiersin.org
Leptin, a pleiotropic protein has long been recognized to play an important role in the
regulation of energy homeostasis, metabolism, neuroendocrine function, and other …

Obesity and lung inflammation

P Mancuso - Journal of applied physiology, 2010 - journals.physiology.org
The prevalence of obesity has increased dramatically worldwide, predisposing individuals to
an increased risk of morbidity and mortality due to cardiovascular disease and type 2 …