Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

Although the normal physiological level of oxidative stress is beneficial for maintaining bone
homeostasis, imbalance between reactive oxygen species (ROS) production and …

During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …

Background Osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs)
is an essential event in alveolar bone regeneration. Oxidative stress may be the main …

7-Ketocholesterol (7KC) is one of the oxysterols produced by the auto-oxidation of
cholesterol during the dysregulation of cholesterol metabolism which has been implicated in …

Abstract Hydrogen peroxide (H 2 O 2), superoxide anion radical (O 2− radical dot), and other
forms of reactive oxygen species (ROS) are produced by the vast majority of mammalian …

Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular
senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The …

Reactive oxygen species (ROS) are natural products of mitochondrial oxidative metabolism
and oxidative protein folding. ROS levels must be well controlled, since elevated ROS has …

Background: Osteoporosis is an important medical and social public health problem in an
aging or elderly society. Osteoporosis is caused by an imbalance in bone remodeling, which …