Recent experimental and clinical studies have shown that the epicardial autonomic ganglia
play an important role in the initiation and maintenance of atrial fibrillation (AF). In this …

Evidence for clinically meaningful benefits of transcutaneous vagus nerve stimulation (VNS)
has been rapidly accumulating over the past 15 years. This relatively novel non-invasive …

Heart rate variability (HRV) is a non-invasive method to measure cardiac autonomic
function. Impairments in HRV have been proposed as independent risk factor for increased …

The sympathetic nervous system is crucial for controlling multiple cardiac functions.
However, a comprehensive, detailed neuroanatomical map of the sympathetic innervation of …

Dysfunction of the intrinsic cardiac nervous system is implicated in the genesis of atrial and
ventricular arrhythmias. While this system has been studied extensively in animal models …

The cardiac pacemaker ignites and coordinates the contraction of the whole heart,
uninterruptedly, throughout our entire life. Pacemaker rate is constantly tuned by the …

We have developed and integrated several technologies including whole-organ imaging
and software development to support an initial precise 3D neuroanatomical mapping and …

An ageing myocardium possesses significant electrophysiological alterations that
predisposes the elderly patient to arrhythmic risk. Whilst these alterations are intrinsic to the …

The aim of this study was to investigate autonomic cardiac control in patients with
amyotrophic lateral sclerosis (ALS). Fifty-five patients with sporadic ALS (28 female and 27 …

Although the rabbit is routinely used as the animal model of choice to investigate cardiac
electrophysiology, the neuroanatomy of the rabbit heart is not well documented. The aim of …