Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Infection of humans with SARS‐CoV‐2 virus causes a disease known colloquially as
“COVID‐19” with symptoms ranging from asymptomatic to severe pneumonia. Initial …

Major depressive disorder (MDD) is a life‐threatening illness characterized by mood
changes and high rates of suicide. Although the role of neuroinflammation in MMD has been …

Transdermal drug delivery is of vital importance for medical treatments. However, user
adherence to long-term repetitive drug delivery poses a grand challenge. Furthermore, the …

Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal
environment with the photoperiod. It is synthesized in the pineal gland and greatly depends …

Depression has become one of the most commonly prevalent neuropsychiatric disorders,
and the main characteristics of depression are sleep disorders and melatonin secretion …

Melatonin (MEL) is a pleiotropic indolamine that reaches multiple intracellular targets.
Among these, MEL binds to calmodulin (CaM) with high affinity. In presence of Ca2+, CaM …

Throughout the reproductive cycle in rodents, prolactin levels are generally low. In some
species, including rats, a prolactin surge occurs on proestrus with peak concentrations …

Given the devastating social and health consequences of drug addiction and the limitations
of current treatments, a new strategy is needed. Circadian system disruptions are frequently …

Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine secreted by the pineal gland
during the dark phase of the photoperiod. Its main function is the synchronization of different …