Corneal stromal repair and regeneration

RR Mohan, D Kempuraj, S D'Souza, A Ghosh - Progress in retinal and eye …, 2022 - Elsevier
The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

Clinical applications of anterior segment optical coherence tomography: An updated review

YJ Chong, M Azzopardi, G Hussain, A Recchioni… - Diagnostics, 2024 - mdpi.com
Since its introduction, optical coherence tomography (OCT) has revolutionized the field of
ophthalmology and has now become an indispensable, noninvasive tool in daily practice …

Low Energy Blue Pulsed Light‐Activated Injectable Materials for Restoring Thinning Corneas

AJ MacAdam, M Munoz, JE Hage, K Hu… - Advanced Functional …, 2023 - Wiley Online Library
Many alternatives to human donor corneas are being developed to meet the global shortage
of donated tissues. However, corneal transplantation remains the gold standard for diseases …

Biomechanics of keratoconus: Two numerical studies

N Falgayrettes, E Patoor, F Cleymand, Y Zevering… - PloS one, 2023 - journals.plos.org
Background The steep cornea in keratoconus can greatly impair eyesight. The etiology of
keratoconus remains unclear but early injury that weakens the corneal stromal architecture …

Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for …

C Dittfeld, C Welzel, U König, A Jannasch… - Biomaterials …, 2023 - Elsevier
Hemocompatibility tuning was adopted to explore and refine an innovative, GA-free
preparation strategy combining decellularization, riboflavin/UV crosslinking, and low-energy …

Controlled drug delivery device for cornea treatment and novel method for its testing

P Urbánek, P Šuly, J Ševčík, B Hanulíková, I Kuřitka… - Pharmaceuticals, 2023 - mdpi.com
A new solution for local anesthetic and antibiotic delivery after eye surgery is presented. A
contact lens-shaped collagen drug carrier was created and loaded by Levofloxacin and …

Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus

XF Li, SL Luo, Z Wang, YY Miao, MM Zhu… - Computers in Biology …, 2023 - Elsevier
Propose To establish a dynamic topography analysis method which simulates the dynamic
biomechanical response of the cornea and reveals the variations of such response within …

Dynamic evaluation of corneal cross-linking and osmotic diffusion effects using optical coherence elastography

M Frigelli, P Büchler, S Kling - Scientific reports, 2024 - nature.com
Dynamic deformation events induced by osmosis or photochemical stiffening substantially
influence geometrical and mechanical assessments in post-mortem corneas, therefore need …

CorNet: Autonomous feature learning in raw Corvis ST data for keratoconus diagnosis via residual CNN approach

PP Zhang, LT Yang, YC Mao, XY Zhang… - Computers in Biology …, 2024 - Elsevier
Purpose To ascertain whether the integration of raw Corvis ST data with an end-to-end CNN
can enhance the diagnosis of keratoconus (KC). Method The Corvis ST is a non-contact …

[HTML][HTML] Management of corneal neovascularization: Current and emerging therapeutic approaches

D Wu, KE Chan, BXH Lim, DKA Lim… - Indian Journal of …, 2024 - journals.lww.com
Corneal neovascularization (CoNV) is a sight-threatening condition affecting an estimated
1.4 million people per year, and the incidence is expected to rise. It is a complication of …