Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …

The decrease in mortality and improved outcome for patients with severe traumatic brain
injury over the past 25 years can be attributed to the approach of" squeezing oxygenated …

BACKGROUND: Corticosteroids have been used to treat head injuries for more than 30
years. In 1997, findings of a systematic review suggested that these drugs reduce risk of …

Traumatic Brain Injury (TBI) affects a large proportion and extensive array of individuals in
the population. While precise pathological mechanisms are lacking, the growing base of …

Guidelines for the management of severe head injury Page 1 EUROPEAN JOURNAL OF
EMERGENCY MEDICINE, 1996. 2. 109-127 v GUIDELINES Guidelines for the …

Object In spite of evidence that use of the Brain Trauma Foundation Guidelines for the
Management of Severe Traumatic Brain Injury (Guidelines) would dramatically reduce …

Background Raised intracranial pressure (ICP) is an important complication of severe brain
injury, and is associated with high mortality. Barbiturates are believed to reduce ICP by …

Background Mannitol is sometimes effective in reversing acute brain swelling, but its
effectiveness in the ongoing management of severe head injury remains unclear. There is …

Objective The purpose of this study was three-fold: a) to examine variations in care of
patients with severe head injury in academic trauma centers across the United States; b) to …