The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Numerous tissue regeneration paradigms show evident neurological dependence, including
mammalian fingertip, skin, and bone regeneration. The mature skeleton is innervated by an …

Type 2 diabetes with obesity-related insulin resistance as the main manifestation is
associated with an increased risk of cognitive impairment. Adipose tissue plays an important …

The regeneration of bone defects in patients with diabetes mellitus (DM) is remarkably
impaired by hyperglycemia and over-expressed proinflammatory cytokines, proteinases …

Angiogenesis is closely coupled with osteogenesis and has equal importance. Thus,
promoting angiogenesis during the bone repair process is vital for ideal bone regeneration …

The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Osteoarthritis (OA) is a degenerative joint disorder causing pain and functional disability.
Emerging evidence reveals that circular RNAs (circRNAs) play essential roles in OA …

MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

The development of green and efficient deuteration methods is of great significance for
various fields such as organic synthesis, analytical chemistry, and medicinal chemistry …

The intricate, hostile, and diverse nature of osteomyelitis (OM) poses a challenge for
complete bacterial eradication and osteogenesis promotion via conventional treatment …