[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?
V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Individuals with obesity and COVID‐19: a global perspective on the epidemiology and biological relationships
BM Popkin, S Du, WD Green, MA Beck… - Obesity …, 2020 - Wiley Online Library
The linkage of individuals with obesity and COVID‐19 is controversial and lacks systematic
reviews. After a systematic search of the Chinese and English language literature on COVID …
reviews. After a systematic search of the Chinese and English language literature on COVID …
[HTML][HTML] Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation
Age is a non-modifiable risk factor for the inflammation that underlies age-associated
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
[HTML][HTML] Post-acute sequelae of COVID-19: A metabolic perspective
The SARS-CoV-2 pandemic continues to rage around the world. At the same time, despite
strong public health measures and high vaccination rates in some countries, a post-COVID …
strong public health measures and high vaccination rates in some countries, a post-COVID …
[HTML][HTML] The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases
A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …
protection against internal and external threats, but can secondarily damage host tissues …
Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
[HTML][HTML] Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond
R Liu, BS Nikolajczyk - Frontiers in immunology, 2019 - frontiersin.org
Obesity-associated inflammation stems from a combination of cell-intrinsic changes of
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …
Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities
S SantaCruz-Calvo, L Bharath, G Pugh… - Nature Reviews …, 2022 - nature.com
Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …
decreases in physical activity levels and a shift to diets that include addictive and/or high …
[HTML][HTML] Role of innate and adaptive immunity in obesity-associated metabolic disease
T McLaughlin, SE Ackerman, L Shen… - The Journal of …, 2017 - Am Soc Clin Investig
Chronic inflammation in adipose tissue, possibly related to adipose cell hypertrophy,
hypoxia, and/or intestinal leakage of bacteria and their metabolic products, likely plays a …
hypoxia, and/or intestinal leakage of bacteria and their metabolic products, likely plays a …
[HTML][HTML] The alterations in and the role of the Th17/Treg balance in metabolic diseases
S Zhang, X Gang, S Yang, M Cui, L Sun, Z Li… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammation plays an important role in the development of metabolic diseases.
These include obesity, type 2 diabetes mellitus, and metabolic dysfunction-associated fatty …
These include obesity, type 2 diabetes mellitus, and metabolic dysfunction-associated fatty …