Nanomaterials for mRNA‐based therapeutics: Challenges and opportunities

D Li, Q Liu, M Yang, H Xu, M Zhu… - Bioengineering & …, 2023 - Wiley Online Library
Messenger RNA (mRNA) holds great potential in developing immunotherapy, protein
replacement, and genome editing. In general, mRNA does not have the risk of being …

Recent advancements in design of nucleic acid nanocarriers for controlled drug delivery

RJ Mosley, B Rucci, ME Byrne - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Research of nanoscale nucleic acid carriers has garnered attention in recent years due to
their distinctive and controllable properties. However, current knowledge is limited in how …

Targeted drug delivery using a plug-to-direct antibody–nanogel conjugate

U Huynh, P Wu, J Qiu, T Prachyathipsakul… - …, 2023 - ACS Publications
Targeted drug delivery using antibody–drug conjugates has attracted great attention due to
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …

Protein-based nanoparticles for therapeutic nucleic acid delivery

F Eweje, ML Walsh, K Ahmad, V Ibrahim, A Alrefai… - Biomaterials, 2024 - Elsevier
To realize the full potential of emerging nucleic acid therapies, there is a need for effective
delivery agents to transport cargo to cells of interest. Protein materials exhibit several unique …

Emerging lipid–polymer hybrid nanoparticles for genome editing

M Gameiro, JF Mano, VM Gaspar - Polymer Chemistry, 2024 - pubs.rsc.org
Genome editing technologies have been key to unlocking new bioengineering strategies as
they enable the modification of mammalian cells' genes in a fully user-programmed mode …

Lipid nanoparticle-based formulations for high-performance dentistry applications

I Mutreja, D Kumar, A Kaushik… - Journal of Materials …, 2023 - pubs.rsc.org
In the growing field of dentistry research, there is significant scope for investigating novel
and high-performance functional biomaterials for dental care, mainly to combat oral health …

Photoswitchable polyurethane based nanoaggregates for on-command release of noncovalent guest molecules

S Kolay, A Mondal, SM Ali, S Santra… - … Science, Part A, 2022 - Taylor & Francis
The self-assembly of light responsive amphiphilic polymers has been of great interest in
spatially and temporally controlled drug delivery applications. In this article, we report the …

[HTML][HTML] Peritoneal B Cells Play a Role in the Production of Anti-polyethylene Glycol (PEG) IgM against Intravenously Injected siRNA-PEGylated Liposome Complexes

T Shimizu, ASA Lila, Y Kitayama, R Abe… - Biological and …, 2024 - jstage.jst.go.jp
Abstract Polyethylene glycol (PEG)-modified (PEGylated) cationic liposomes are frequently
used as delivery vehicles for small interfering RNA (siRNA)-based drugs because of their …

Uncovering the Emerging Prospects of Lipid-based Nanoparticulate Vehicles in Lung Cancer Management: A Recent Perspective

DS Gupta, D Suares - Pharmaceutical Nanotechnology, 2025 - benthamdirect.com
Lung cancer, a leading cause of cancer-related deaths globally, is gaining research interest
more than ever before. Owing to the burden of pathogenesis on the quality of life of patients …

DEVELOPMENT OF BIOMOLECULE NANOPARTICLE CONJUGATE FOR TARGETED DELIVERY OF THERAPEUTICS

P Wu - 2023 - scholarworks.umass.edu
Delivery of therapeutics specifically to the disease site is the final goal for the field of drug
discovery. Considerable efforts in understanding disease biology have contributed to …