The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …

Epithelial–mesenchymal transition (EMT) is a cellular programme that is known to be crucial
for embryogenesis, wound healing and malignant progression. During EMT, cell–cell and …

Epithelial–mesenchymal transition (EMT) has been implicated in various aspects of tumor
development, including tumor invasion and metastasis, cancer stemness, and therapy …

Tumor growth and progression are the products of complex signaling networks between
different cell types within the tumor and its surrounding stroma. In particular, established …

The dynamic interplay between neoplastic cells and the immune microenvironment
regulates every step of the metastatic process. Immune cells contribute to invasion by …

Carcinoma cells that undergo an epithelial-mesenchymal transition (EMT) and display a
predominantly mesenchymal phenotype (hereafter EMT tumor cells) are associated with …

Simple Summary Pancreatic ductal adenocarcinoma's (PDAC) dismal prognosis is
associated with its aggressive biological behavior and resistance to chemotherapy …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is still one of the deadliest
cancers in western countries. It is commonly diagnosed at advanced stages and most anti …

Tumor cell plasticity is a major obstacle for the cure of malignancies as it makes tumor cells
highly adaptable to microenvironmental changes, enables their phenotype switching among …

Infection with Helicobacter pylori, a Gram-negative, microaerophilic pathogen often results in
gastric cancer in a subset of affected individuals. This explains why H. pylori is the only …