Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …

Adipose tissue exhibits a remarkable capacity to expand, contract, and remodel in response
to changes in physiological and environmental conditions. Here, we describe recent …

The circadian clock plays an essential role in coordinating feeding and metabolic rhythms
with the light/dark cycle. Disruption of clocks is associated with increased adiposity and …

White adipose tissue (WAT) development and adult homeostasis rely on distinct adipocyte
progenitor cells (APCs). While adult APCs are defined early during embryogenesis and …

De novo brown adipogenesis holds potential in combating the epidemics of obesity and
diabetes. However, the identity of brown adipocyte progenitor cells (APCs) and their …

Background Obesity is associated with extensive white adipose tissue (WAT) expansion and
remodeling. Healthy WAT expansion contributes to the maintenance of energy balance in …

The development of white adipose tissue (WAT) occurs during distinct embryonic and
postnatal stages, and it is subsequently maintained throughout life. However, the specific …

Adipose tissue plasticity is orchestrated by molecularly and functionally diverse cells within
the stromal vascular fraction (SVF). Although several mouse and human adipose SVF …

Progress has been made in identifying stem cell aging as a pathological manifestation of a
variety of diseases, including obesity. Adipose stem cells (ASCs) play a core role in …

The hypothalamus and the white adipose tissue are both key regulator of energy
homeostasis. The hypothalamus is the central hub in metabolic control and links the …