Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery

G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials

X Du, J Zhou, J Shi, B Xu - Chemical reviews, 2015 - ACS Publications
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

On the nature of biomaterials

DF Williams - Biomaterials, 2009 - Elsevier
The situations in which biomaterials are currently used are vastly different to those of just a
decade ago. Although implantable medical devices are still immensely important, medical …

Mimicking the cell: bio-inspired functions of supramolecular assemblies

Y Tu, F Peng, A Adawy, Y Men… - Chemical …, 2016 - ACS Publications
The successful assembly of large supramolecular structures infers a delicate balance
between reversible noncovalent interactions which are capable of undergoing correction …

Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications

KJ Skilling, F Citossi, TD Bradshaw, M Ashford… - Soft matter, 2014 - pubs.rsc.org
In recent years low molecular mass organic gelators (LMOGs) have gained increasing
interest as an alternative biomaterial to polymer derived gels, with potential applications in …

Control of molecular gelation by chemical stimuli

MD Segarra-Maset, VJ Nebot, JF Miravet… - Chemical Society …, 2013 - pubs.rsc.org
Molecular gels are formed by the self-assembly of low-molecular weight compounds by
weak non-covalent interactions and thus, they may be easily disassembled in response to …

Release of small bioactive molecules from physical gels

J Mayr, C Saldías, DD Díaz - Chemical Society Reviews, 2018 - pubs.rsc.org
Pharmaceutical drugs with low water solubility have always received great attention within
the scientific community. The reduced bioavailability and the need of frequent …

Molecular hydrogels of therapeutic agents

F Zhao, ML Ma, B Xu - Chemical Society Reviews, 2009 - pubs.rsc.org
This tutorial review aims to introduce a new kind of biomaterials—molecular hydrogels of
therapeutic agents. Based on the molecular self-assembly in water, it is possible to transform …

Dephosphorylation of d-Peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/Hydrogels and Their Potential Applications for Intracellular Imaging …

J Li, Y Gao, Y Kuang, J Shi, X Du, J Zhou… - Journal of the …, 2013 - ACS Publications
d-Peptides, as the enantiomers of the naturally occurring l-peptides, usually resist
endogenous proteases and are presumably insensitive to most enzymes. But, it is unclear …