[HTML][HTML] Is cancer biology different in older patients?

Y Van Herck, A Feyaerts, S Alibhai… - The Lancet Healthy …, 2021 - thelancet.com
Roughly 50% of cancer cases occur in people aged 65 years or older. Older people are
often diagnosed at a later stage and might receive less (intensive) treatment, which might …

Older adults with cancer and their caregivers—current landscape and future directions for clinical care

S Kadambi, KP Loh, R Dunne, A Magnuson… - Nature Reviews …, 2020 - nature.com
Despite substantial improvements in the outcomes of patients with cancer over the past two
decades, older adults (aged≥ 65 years) with cancer are a rapidly increasing population and …

Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment

E Ramsdale, M Mohamed, V Yu, E Otto, K Juba… - The …, 2022 - academic.oup.com
Purpose Polypharmacy is prevalent in older adults starting cancer treatment and associated
with potentially inappropriate medications (PIM), potential drug-drug interactions (DDI), and …

Association of polypharmacy and potential drug‐drug interactions with adverse treatment outcomes in older adults with advanced cancer

MR Mohamed, SG Mohile, KM Juba, H Awad, M Wells… - Cancer, 2023 - Wiley Online Library
Background Polypharmacy is common in older adults who are starting cancer treatment and
is associated with an increased risk of potentially inappropriate medications (PIMs) and …

[HTML][HTML] Understanding treatment tolerability in older adults with cancer

MA Flannery, E Culakova, BE Canin… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The treatment cannot be worse than the disease is an oft-cited statement representing the
important concept of tolerability; older patients often express concerns about side effects …

[HTML][HTML] Prevalence of polypharmacy, hyperpolypharmacy and potentially inappropriate medication use in older adults in India: a systematic review and meta-analysis

AS Bhagavathula, K Vidyasagar, M Chhabra… - Frontiers in …, 2021 - frontiersin.org
Background: Older people often receive multiple medications for chronic conditions, which
often result in polypharmacy (concomitant use of 5‒9 medicines) and hyperpolypharmacy …

[HTML][HTML] Prevalence of polypharmacy and potentially inappropriate medications use in elderly Chinese patients: a systematic review and meta-analysis

F Tian, Z Chen, J Wu - Frontiers in Pharmacology, 2022 - frontiersin.org
Objectives: Polypharmacy and potentially inappropriate medication (PIM) use among elderly
Chinese patients have not yet been investigated by systematic review and meta-analysis …

Prevalence of polypharmacy and risks of potentially inappropriate medication use in the older population in a developing country: a systematic review and meta …

AS Bhagavathula, EA Gebreyohannes, D Fialova - Gerontology, 2022 - karger.com
Abstract Background and Aim: Polypharmacy and potentially inappropriate medication (PIM)
use in older populations (65+ years) have not yet been investigated by meta-analyses in …

Association of polypharmacy and potentially inappropriate medications with frailty among older adults with blood cancers

TT Hshieh, C DuMontier, T Jaung, NE Bahl… - Journal of the National …, 2022 - jnccn.org
Background: Polypharmacy and potentially inappropriate medications (PIMs) are common
among older adults with blood cancers, but their association with frailty and how to manage …

Systematic review and meta-analysis on the associations of polypharmacy and potentially inappropriate medication with adverse outcomes in older cancer patients

LJ Chen, K Trares, DC Laetsch… - The Journals of …, 2021 - academic.oup.com
Background Both polypharmacy and potentially inappropriate medication (PIM) intake are
highly prevailing in older cancer patients. However, only studies on the association of …