Snake venom peptides: Tools of biodiscovery

A Munawar, SA Ali, A Akrem, C Betzel - Toxins, 2018 - mdpi.com
Nature endowed snakes with a lethal secretion known as venom, which has been fine-tuned
over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive …

Hypotensive snake venom components—a mini-review

O Péterfi, F Boda, Z Szabó, E Ferencz, L Bába - Molecules, 2019 - mdpi.com
Hypertension is considered a major public health issue due to its high prevalence and
subsequent risk of cardiovascular and kidney diseases. Thus, the search for new …

Snake venom components: tools and cures to target cardiovascular diseases

J Frangieh, M Rima, Z Fajloun, D Henrion, JM Sabatier… - Molecules, 2021 - mdpi.com
Cardiovascular diseases (CVDs) are considered as a major cause of death worldwide.
Therefore, identifying and developing therapeutic strategies to treat and reduce the …

Snake venom‐derived bradykinin‐potentiating peptides: A promising therapy for COVID‐19?

AS Gouda, B Mégarbane - Drug Development Research, 2021 - Wiley Online Library
The severe acute respiratory syndrome coronavirus‐2 (SARS‐COV‐2), a novel coronavirus
responsible for the recent infectious pandemic, is known to downregulate angiotensin …

Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms

D Mora-Obando, D Pla, B Lomonte… - PLoS Neglected …, 2021 - journals.plos.org
Background Bothrops asper represents the clinically most important snake species in
Central America and Northern South America, where it is responsible for an estimated 50 …

Proteome and Peptidome of Vipera berus berus Venom

A Bocian, M Urbanik, K Hus, A Łyskowski, V Petrilla… - Molecules, 2016 - mdpi.com
Snake venom is a rich source of peptides and proteins with a wide range of actions. Many of
the venom components are currently being tested for their usefulness in the treatment of …

Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

VC Carregari, L Rosa-Fernandes, P Baldasso… - Scientific reports, 2018 - nature.com
Proteins constitute almost 95% of snake venom's dry weight and are produced and released
by venom glands in a solubilized form during a snake bite. These proteins are responsible …

Separation and Analytical Techniques Used in Snake Venomics: A Review Article

C Sahyoun, M Rima, C Mattei, JM Sabatier, Z Fajloun… - Processes, 2022 - mdpi.com
The deleterious consequences of snake envenomation are due to the extreme protein
complexity of snake venoms. Therefore, the identification of their components is crucial for …

Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia

A Rodríguez-Vargas, N Vega, E Reyes-Montaño… - Toxins, 2022 - mdpi.com
Biochemical and biological differences in the venom of Crotalus durissus cumanensis from
three ecoregions of Colombia were evaluated. Rattlesnakes were collected from the …

Snake Venom Components as Therapeutic Drugs in Ischemic Heart Disease

E Messadi - Biomolecules, 2023 - mdpi.com
Ischemic heart disease (IHD), especially myocardial infarction (MI), is a leading cause of
death worldwide. Although coronary reperfusion is the most straightforward treatment for …