Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

[HTML][HTML] Racial disparities in triple negative breast cancer: a review of the role of biologic and non-biologic factors

O Prakash, F Hossain, D Danos, A Lassak… - Frontiers in Public …, 2020 - frontiersin.org
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks
expression of the estrogen receptor (ER), progesterone receptor (PR), and human …

Relationship of established risk factors with breast cancer subtypes

AM McCarthy, T Friebel‐Klingner, S Ehsan… - Cancer …, 2021 - Wiley Online Library
Background Breast cancer is a heterogeneous disease, divided into subtypes based on the
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

[HTML][HTML] Contribution of adipose tissue to development of cancer

AJ Cozzo, AM Fuller, L Makowski - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …

[HTML][HTML] Obesity and survival among a cohort of breast cancer patients is partially mediated by tumor characteristics

CK Blair, CL Wiggins, AM Nibbe, CB Storlie… - NPJ breast …, 2019 - nature.com
Obesity exerts adverse effects on breast cancer survival, but the means have not been fully
elucidated. We evaluated obesity as a contributor to breast cancer survival according to …

[HTML][HTML] Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: a dose-response meta-analysis with 3,318,796 subjects …

Y Chen, L Liu, Q Zhou, MU Imam, J Cai, Y Wang… - BMC Public Health, 2017 - Springer
Background There is sufficient evidence supporting a relationship between increased body
mass index (BMI) and an increased risk for breast cancer among postmenopausal women …

Microbiome, bile acids, and obesity: How microbially modified metabolites shape anti‐tumor immunity

LM Sipe, M Chaib, AK Pingili, JF Pierre… - Immunological …, 2020 - Wiley Online Library
Bile acids (BAs) are known facilitators of nutrient absorption but recent paradigm shifts now
recognize BAs as signaling molecules regulating both innate and adaptive immunity. Bile …

Obesity and breast cancer in premenopausal women: Current evidence and future perspectives

D Laudisio, G Muscogiuri, L Barrea… - European Journal of …, 2018 - Elsevier
There is raising evidence reporting an increased incidence of breast cancer over the past
decades. Every year approximately 1.4 million new cases of breast cancer are diagnosed …

[HTML][HTML] The molecular and genetic interactions between obesity and breast cancer risk

GMA Ajabnoor - Medicina, 2023 - mdpi.com
Breast cancer (BC) is considered the leading cause of death among females worldwide.
Various risk factors contribute to BC development, such as age, genetics, reproductive …

[HTML][HTML] Body mass index, mammographic density, and breast cancer risk by estrogen receptor subtype

Y Shieh, CG Scott, MR Jensen, AD Norman… - Breast Cancer …, 2019 - Springer
Background Obesity and elevated breast density are common risk factors for breast cancer,
and their effects may vary by estrogen receptor (ER) subtype. However, their joint effects on …