[HTML][HTML] Multiple roles of fucoxanthin and astaxanthin against Alzheimer's disease: Their pharmacological potential and therapeutic insights
Alzheimer's disease (AD) is the most devastating neurodegenerative disorder affecting the
elderly. The exact pathology of AD is not yet fully understood and several hallmarks such as …
elderly. The exact pathology of AD is not yet fully understood and several hallmarks such as …
Astaxanthin from crustaceans and their byproducts: a bioactive metabolite candidate for therapeutic application
In recent years, the food, pharma, and cosmetic industries have shown considerable interest
in bioactive molecules of marine origin that show high potential for application as …
in bioactive molecules of marine origin that show high potential for application as …
The role of astaxanthin as a nutraceutical in health and age-related conditions
The current review provides an up-to-date analysis of scientific data on astaxanthin (ASX)
sources and experimental studies on its health benefits as a potent antioxidant in the aging …
sources and experimental studies on its health benefits as a potent antioxidant in the aging …
[HTML][HTML] Cheminformatics Identification of Phenolics as Modulators of Penicillin-Binding Protein 2a of Staphylococcus aureus: A Structure–Activity-Relationship-Based …
JO Aribisala, S Sabiu - Pharmaceutics, 2022 - mdpi.com
The acquisition of penicillin-binding protein (PBP) 2a in resistant strains of Staphylococcus
aureus allows for the continuous production of cell walls even after the inactivation of …
aureus allows for the continuous production of cell walls even after the inactivation of …
[HTML][HTML] Astaxanthin: a promising therapeutic agent for organ fibrosis
K Li, W Wang, W Xiao - Pharmacological Research, 2023 - Elsevier
Fibrosis is the end-stage pathological manifestation of many chronic diseases. Infiltration of
inflammatory cells and activation of myofibroblasts are the most prominent features of …
inflammatory cells and activation of myofibroblasts are the most prominent features of …
Identification of secondary metabolites from Crescentia cujete as promising antibacterial therapeutics targeting type 2A topoisomerases through molecular dynamics …
JO Aribisala, RA Abdulsalam, Y Dweba… - Computers in Biology …, 2022 - Elsevier
The potential of fluoroquinolones as remarkable antibacterial agents evolved from their
ability to generate 'poison'complexes between type IIA topoisomerases [topo2As (DNA …
ability to generate 'poison'complexes between type IIA topoisomerases [topo2As (DNA …
Molecular modelling identification of phytocompounds from selected African botanicals as promising therapeutics against druggable human host cell targets of SARS …
Abstract The coronavirus disease 2019 (COVID-19), caused by the Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly pathogenic and …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly pathogenic and …
Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV …
AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Despite the existence of some vaccines, SARS-CoV-2 (S-2) infections persist for various
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …
Redox impact on bacterial macromolecule: a promising avenue for discovery and development of novel antibacterials
JO Aribisala, S Sabiu - Biomolecules, 2022 - mdpi.com
Antibiotic resistance in bacteria has remained a serious public health concern, resulting in
substantial deaths and morbidity each year. Factors such as mutation and abuse of currently …
substantial deaths and morbidity each year. Factors such as mutation and abuse of currently …
Waste to Medicine: Evidence from Computational Studies on the Modulatory Role of Corn Silk on the Therapeutic Targets Implicated in Type 2 Diabetes Mellitus
Simple Summary Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance
and/or defective insulin production in the human body. Corn silk (CS), an abundant, readily …
and/or defective insulin production in the human body. Corn silk (CS), an abundant, readily …