Evolution of cancer pharmacological treatments at the turn of the third millennium
The medical history of cancer began millennia ago. Historical findings of patients with
cancer date back to ancient Egyptian and Greek civilizations, where this disease was …
cancer date back to ancient Egyptian and Greek civilizations, where this disease was …
[HTML][HTML] Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”), a condition that significantly impairs the quality of life of …
X Ren, D Boriero, L Chaiswing, S Bondada… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Increasing numbers of cancer patients survive and live longer than five years after therapy,
but very often side effects of cancer treatment arise at same time. One of the side effects …
but very often side effects of cancer treatment arise at same time. One of the side effects …
Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation
M Anoud, E Delagoutte, Q Helleu, A Brion… - Elife, 2024 - elifesciences.org
Tardigrades are microscopic animals renowned for their ability to withstand extreme
conditions, including high doses of ionizing radiation (IR). To better understand their radio …
conditions, including high doses of ionizing radiation (IR). To better understand their radio …
[HTML][HTML] An RNA repair operon regulated by damaged tRNAs
KJ Hughes, X Chen, AM Burroughs, L Aravind… - Cell reports, 2020 - cell.com
Many bacteria contain an RNA repair operon, encoding the RtcB RNA ligase and the RtcA
RNA cyclase, that is regulated by the RtcR transcriptional activator. Although RtcR contains …
RNA cyclase, that is regulated by the RtcR transcriptional activator. Although RtcR contains …
Expression of a Tardigrade Dsup Gene Enhances Genome Protection in Plants
J Kirke, XL Jin, XH Zhang - Molecular Biotechnology, 2020 - Springer
DNA damage is one of the most impactful events in living organisms, leading to DNA
sequence changes (mutation) and disruption of biological processes. A study has identified …
sequence changes (mutation) and disruption of biological processes. A study has identified …
The interaction of the metallo-glycopeptide anti-tumour drug bleomycin with DNA
V Murray, JK Chen, LH Chung - International journal of molecular …, 2018 - mdpi.com
The cancer chemotherapeutic drug, bleomycin, is clinically used to treat several neoplasms
including testicular and ovarian cancers. Bleomycin is a metallo-glycopeptide antibiotic that …
including testicular and ovarian cancers. Bleomycin is a metallo-glycopeptide antibiotic that …
Treatment of spontaneous canine mast cell tumors by electrochemotherapy combined with IL-12 gene electrotransfer: Comparison of intratumoral and peritumoral …
UL Tratar, N Milevoj, M Cemazar, K Znidar… - International …, 2023 - Elsevier
The combined treatment of electrochemotherapy (ECT) and interleukin-12 (IL-12) gene
electrotransfer (GET) has already been used in clinical studies in dogs to treat various …
electrotransfer (GET) has already been used in clinical studies in dogs to treat various …
[HTML][HTML] Changes in plasma IL-1β, TNF-α and IL-4 levels are involved in chemotherapy-related cognitive impairment in early-stage breast cancer patients
J Zhao, H Zuo, K Ding, X Zhang, Z Bi… - American journal of …, 2020 - ncbi.nlm.nih.gov
To investigate changes in cytokine (IL-1β, TNF-α and IL-4) levels before and after
chemotherapy and their correlation with cognitive impairment in early-stage breast cancer …
chemotherapy and their correlation with cognitive impairment in early-stage breast cancer …
Bleomycin revisited: a direct comparison of the intratracheal micro-spraying and the oropharyngeal aspiration routes of bleomycin administration in mice
I Barbayianni, I Ninou, A Tzouvelekis, V Aidinis - Frontiers in Medicine, 2018 - frontiersin.org
Idiopathic Pulmonary Fibrosis (IPF) is a fatal disease characterized by exuberant deposition
of extracellular matrix components, deterioration of lung architecture and impairment of lung …
of extracellular matrix components, deterioration of lung architecture and impairment of lung …
Enrichment of stem cell-derived pancreatic beta-like cells and controlled graft size through pharmacological removal of proliferating cells
AH Shilleh, S Beard, HA Russ - Stem Cell Reports, 2023 - cell.com
Transplantation of limited human cadaveric islets into type 1 diabetic patients results in∼ 35
months of insulin independence. Direct differentiation of stem cell-derived insulin-producing …
months of insulin independence. Direct differentiation of stem cell-derived insulin-producing …