Recent advances in low-frequency Raman spectroscopy for pharmaceutical applications
Low-frequency Raman (LFR) spectroscopy probes vibrational modes related to long-range
order (ie, crystallinity) that can provide unique information on the solid-state/structural …
order (ie, crystallinity) that can provide unique information on the solid-state/structural …
[HTML][HTML] Opportunities for milk and milk-related systems as 'new'low-cost excipient drug delivery materials
Milk is well recognised as an amazing delivery system for essential lipids, poorly soluble
nutrients, sugars, amino acids and delivery of critical biological molecules to sustain the …
nutrients, sugars, amino acids and delivery of critical biological molecules to sustain the …
In Operando Analysis of Milk-Based Oral Formulations during Digestion Using Synchrotron Small-Angle X-ray Scattering Coupled to Low-Frequency Raman …
K Be̅rziņš, P Meiland, A Aljabbari… - Analytical …, 2024 - ACS Publications
A low-frequency Raman (LFR) probe was coupled to an in-line small-angle X-ray scattering
(SAXS) beamline to test the capabilities of a combinatory approach for the determination of …
(SAXS) beamline to test the capabilities of a combinatory approach for the determination of …
The influence of gastrointestinal biomolecules on solid-state transformations in pharmaceutical particulates
Adsorption of gut relevant biomolecules onto particles after oral administration of solid oral
dosage forms is expected to form a “gastrointestinal corona”, which could influence solution …
dosage forms is expected to form a “gastrointestinal corona”, which could influence solution …
[HTML][HTML] Emerging challenges in assessing bio-based nanosystems' behaviour under in vitro digestion focused on food applications–A critical view and future …
D Madalena, JM Fernandes, Z Avelar… - Food Research …, 2022 - Elsevier
The current consumers' demand for high quality food products together with the growing
awareness regarding the link between health and nutrition has led to the development of …
awareness regarding the link between health and nutrition has led to the development of …
Investigations on the Novel Antimalarial Ferroquine in Biomimetic Solutions Using Deep UV Resonance Raman Spectroscopy and Density Functional Theory
R Domes, T Frosch - Analytical Chemistry, 2023 - ACS Publications
Deep ultraviolet (DUV) resonance Raman experiments are performed, investigating the
novel, promising antimalarial ferroquine (FQ). Two buffered aqueous solutions with pH …
novel, promising antimalarial ferroquine (FQ). Two buffered aqueous solutions with pH …
Solving the computational puzzle: Toward a pragmatic pathway for modeling low-energy vibrational modes of pharmaceutical crystals
Five pharmaceutically relevant compounds with increasing molecular complexity, benzoic
acid, diphenylacetic acid, l-tyrosine, celecoxib (form III), and carvedilol (form II), were …
acid, diphenylacetic acid, l-tyrosine, celecoxib (form III), and carvedilol (form II), were …
Characterization of Variably Substituted Hydroxyapatites Using Low-Frequency Raman Spectroscopy
J Kirkham, TM Korter, K Be̅rziņš… - Crystal Growth & …, 2023 - ACS Publications
Low-frequency Raman spectroscopy was used to characterize variably substituted
hydroxyapatites with Sr2+, F–, and CO32–as the substituting species in the crystalline and …
hydroxyapatites with Sr2+, F–, and CO32–as the substituting species in the crystalline and …
Application of Low-Frequency Raman Spectroscopy to Probe Dynamics of Lipid Mesophase Transformations upon Hydration
Low-frequency Raman (LFR) spectroscopy is presented as a viable tool for studying the
hydration characteristics of lyotropic liquid crystal systems herein. Monoolein was used as a …
hydration characteristics of lyotropic liquid crystal systems herein. Monoolein was used as a …
Monitoring the isothermal dehydration of crystalline hydrates using low-frequency Raman spectroscopy
Detection of the solid-state forms of pharmaceutical compounds is important from the drug
performance point of view. Low-frequency Raman (LFR) spectroscopy has been …
performance point of view. Low-frequency Raman (LFR) spectroscopy has been …