Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancer
The incidence of human papillomavirus-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …
Tumorigenic activation around HPV integrated sites in head and neck squamous cell carcinoma
M Mima, A Okabe, T Hoshii… - … Journal of Cancer, 2023 - Wiley Online Library
Human papillomavirus (HPV) is causally involved in the development of head and neck
squamous cell carcinoma (HNSCC). The integration of HPV drives tumorigenesis through …
squamous cell carcinoma (HNSCC). The integration of HPV drives tumorigenesis through …
Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
Abstract Background Human papillomaviruses (HPVs) induce a subset of head and neck
squamous cell carcinomas (HNSCC) and anogenital cancers, particularly cervical cancer …
squamous cell carcinomas (HNSCC) and anogenital cancers, particularly cervical cancer …
The intratumor bacterial and fungal microbiome is characterized by hpv, smoking, and alcohol consumption in head and neck squamous cell carcinoma
J Chakladar, D John, S Magesh, M Uzelac… - International Journal of …, 2022 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) tumor phenotypes and clinical
outcomes are significantly influenced by etiological agents, such as HPV infection, smoking …
outcomes are significantly influenced by etiological agents, such as HPV infection, smoking …
Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC Reveals Distinct Mechanisms of Carcinogenesis for Fine-scale HPV+ Cancer Subtypes
DNA methylation is a vital early step in carcinogenesis. Most findings of aberrant DNA
methylation in head and neck squamous cell carcinomas (HNSCC) are array based with …
methylation in head and neck squamous cell carcinomas (HNSCC) are array based with …
[HTML][HTML] Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies
M Goswami, J Schlom, RN Donahue - Oncotarget, 2023 - oncotarget.com
With the rapid adoption of immunotherapy into clinical practice for HPV-associated
malignancies, assessing tumor burden using “liquid biopsies” would further our …
malignancies, assessing tumor burden using “liquid biopsies” would further our …
Comprehensive Transcriptome Analysis Reveals the Distinct Gene Expression Patterns of Tumor Microenvironment in HPV-Associated and HPV-Non Associated …
RM Alahmadi, N Marraiki, M Alswayyed, HA Khoja… - Cancers, 2023 - mdpi.com
Simple Summary The tumor microenvironment (TME) of HNSCC is heterogeneous and
complex, and it plays a crucial role in achieving effective cancer therapy. To develop …
complex, and it plays a crucial role in achieving effective cancer therapy. To develop …
Clinical validity of a prognostic gene expression cluster-based model in human papillomavirus–positive oropharyngeal carcinoma
S Cavalieri, MS Serafini, A Carenzo… - JCO precision …, 2021 - ascopubs.org
PURPOSE Under common therapeutic regimens, the prognosis of human papillomavirus
(HPV)–positive squamous oropharyngeal carcinomas (OPCs) is more favorable than HPV …
(HPV)–positive squamous oropharyngeal carcinomas (OPCs) is more favorable than HPV …
p63 directs subtype-specific gene expression in HPV+ head and neck squamous cell carcinoma
AR Glathar, A Oyelakin, C Gluck, J Bard… - Frontiers in …, 2022 - frontiersin.org
The complex heterogeneity of head and neck squamous cell carcinoma (HNSCC) reflects a
diverse underlying etiology. This heterogeneity is also apparent within Human …
diverse underlying etiology. This heterogeneity is also apparent within Human …
Identification of TTC21A as a Potential Prognostic Marker in Head and Neck Squamous Cell Carcinoma: In Silico Analysis
L Wang, Y Yin, P Liu, H Chen… - Cancer Genomics & …, 2024 - cgp.iiarjournals.org
Abstract Background/Aim: Tetratricopeptide repeat domain 21A (TTC21A) plays a crucial
role in ciliary function and has been associated with various pathogenic processes …
role in ciliary function and has been associated with various pathogenic processes …