Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update
R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …
A systematic review of treatment for patients with burning mouth syndrome
HL Tan, JG Smith, J Hoffmann, T Renton - Cephalalgia, 2022 - journals.sagepub.com
Background Burning mouth syndrome is a chronic idiopathic intractable intraoral
dysaesthesia that remains a challenge to clinicians due to its poorly understood …
dysaesthesia that remains a challenge to clinicians due to its poorly understood …
Melatonin: from pharmacokinetics to clinical use in autism spectrum disorder
S Lalanne, C Fougerou-Leurent, GM Anderson… - International Journal of …, 2021 - mdpi.com
The role of melatonin has been extensively investigated in pathophysiological conditions,
including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported …
including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported …
Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies
M Wilhelmsen, I Amirian, RJ Reiter… - Journal of pineal …, 2011 - Wiley Online Library
Melatonin is an endogenous indoleamine, produced mainly by the pineal gland. Melatonin
has been proven to have chronobiotic, antioxidant, antihypertensive, anxiolytic and sedative …
has been proven to have chronobiotic, antioxidant, antihypertensive, anxiolytic and sedative …
Evaluating the oxidative stress in inflammation: role of melatonin
A Sánchez, AC Calpena, B Clares - International journal of molecular …, 2015 - mdpi.com
Oxygen is used by eukaryotic cells for metabolic transformations and energy production in
mitochondria. Under physiological conditions, there is a constant endogenous production of …
mitochondria. Under physiological conditions, there is a constant endogenous production of …
Combination pharmacotherapy for the treatment of fibromyalgia in adults
J Thorpe, B Shum, RA Moore… - Cochrane Database …, 2018 - cochranelibrary.com
Background Fibromyalgia is a chronic widespread pain condition affecting millions of people
worldwide. Current pharmacotherapies are often ineffective and poorly tolerated. Combining …
worldwide. Current pharmacotherapies are often ineffective and poorly tolerated. Combining …
Antidepressants for pain management in adults with chronic pain: a network meta‐analysis
H Birkinshaw, CM Friedrich, P Cole… - Cochrane Database …, 2023 - cochranelibrary.com
Background Chronic pain is common in adults, and often has a detrimental impact upon
physical ability, well‐being, and quality of life. Previous reviews have shown that certain …
physical ability, well‐being, and quality of life. Previous reviews have shown that certain …
An update on pharmacotherapy for the treatment of fibromyalgia
EP Calandre, F Rico-Villademoros… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Fibromyalgia is a syndrome characterized by chronic generalized pain in
addition to different symptoms such as fatigue, sleep disturbances, stiffness, cognitive …
addition to different symptoms such as fatigue, sleep disturbances, stiffness, cognitive …
Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy …
SA de Zanette, R Vercelino, G Laste… - BMC Pharmacology and …, 2014 - Springer
Background Central disinhibition is a mechanism involved in the physiopathology of
fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We …
fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We …
Melatonin: a neurotrophic factor?
A Miranda-Riestra, R Estrada-Reyes… - Molecules, 2022 - mdpi.com
Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal
environment with the photoperiod. It is synthesized in the pineal gland and greatly depends …
environment with the photoperiod. It is synthesized in the pineal gland and greatly depends …