Acetate as a potential feedstock for the production of value-added chemicals: metabolism and applications

Y Kim, S Lama, D Agrawal, V Kumar, S Park - Biotechnology Advances, 2021 - Elsevier
Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …

Metabolism and strategies for enhanced supply of acetyl-CoA in Saccharomyces cerevisiae

Q Zhang, W Zeng, S Xu, J Zhou - Bioresource Technology, 2021 - Elsevier
Acetyl-CoA is a kind of important cofactor that is involved in many metabolic pathways. It
serves as the precursor for many interesting commercial products, such as terpenes …

[HTML][HTML] Metabolic engineering using acetate as a promising building block for the production of bio‐based chemicals

G Gong, B Wu, L Liu, J Li, Q Zhu, M He, G Hu - Engineering Microbiology, 2022 - Elsevier
The production of biofuels and biochemicals derived from microbial fermentation has
received a lot of attention and interest in light of concerns about the depletion of fossil fuel …

Metabolic Engineering of Gas-Fermenting Clostridium ljungdahlii for Efficient Co-production of Isopropanol, 3-Hydroxybutyrate, and Ethanol

D Jia, M He, Y Tian, S Shen, X Zhu, Y Wang… - ACS Synthetic …, 2021 - ACS Publications
Rational design and modification of autotrophic bacteria to efficiently produce high-value
chemicals and biofuels are crucial for establishing a sustainable and economically viable …

Engineering Rhodosporidium toruloides for production of 3-hydroxypropionic acid from lignocellulosic hydrolysate

D Liu, HJ Hwang, PB Otoupal, GM Geiselman… - Metabolic …, 2023 - Elsevier
Microbial production of valuable bioproducts is a promising route towards green and
sustainable manufacturing. The oleaginous yeast, Rhodosporidium toruloides, has emerged …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Enhanced 3-Hydroxypropionic Acid Production From Acetate via the Malonyl-CoA Pathway in Corynebacterium glutamicum

Z Chang, W Dai, Y Mao, Z Cui, Z Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
Acetate is an economical and environmental-friendly alternative carbon source. Herein, the
potential of harnessing Corynebacterium glutamicum as a host to produce 3 …

Recent advances in metabolic engineering of microorganisms for the production of monomeric C3 and C4 chemical compounds

S Zhou, Y Zhang, Z Wei, S Park - Bioresource Technology, 2023 - Elsevier
Bio-based C3 and C4 bi-functional chemicals are useful monomers in biopolymer
production. This review describes recent progresses in the biosynthesis of four such …

Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria

P Zhao, P Tian - World Journal of Microbiology and Biotechnology, 2021 - Springer
Hydroxypropionic acid (3-HP) represents an economically important platform compound
from which a panel of bulk chemicals can be derived. Compared with petroleum-dependent …