Gene expression is regulated at many levels including co-or post-transcriptionally, where
chemical modifications are added to RNA on riboses and bases. Expression control via RNA …

Many studies have highlighted the importance of the tight regulation of mRNA stability in the
control of gene expression. mRNA stability largely depends on the mRNA nucleotide …

Among several known RNA modifications, N6‐methyladenosine (m6A) is the most studied
RNA epitranscriptomic modification and controls multiple cellular functions during …

Abstract The N6‐methyladenosine (m6A) RNA methyltransferase METTL16 is an emerging
player in the RNA modification landscape of the human cell. Originally thought to be a …

Methyltransferase-like protein 16 (METTL16) is a human RNA methyltransferase that installs
m6A marks on U6 small nuclear RNA (U6 snRNA) and S-adenosylmethionine (SAM) …

Abstract N6-methyl-adenosine (m6A) is one of the most common internal modifications on
RNA molecules present in mammalian cells. Deregulation of m6A modification has been …

Several strategies, including chemotherapy and radiotherapy, have improved therapeutic
outcomes among cancer patients in clinical practice. However, due to their heterogeneity …

Despite the discovery of modified nucleic acids nearly 75 years ago, their biological
functions are still being elucidated. N 6‐methyladenosine (m6A) is the most abundant …

Abstract N6-methyladenosine (m6A) and N6, 2′-O-dimethyladenosine (m6Am) are two
abundant modifications found in mRNAs and ncRNAs that can regulate multiple aspects of …

Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in
ensuring cell functions and proper organism development by interacting with cellular …